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CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo.
scientific article published on 29 March 2016
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4812640
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31 March 2020
title
CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4812640
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
author
Li-Chung Tsao
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1
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Europe PubMed Central
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4812640
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
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31 March 2020
Li-Chung Tsao
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5
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Europe PubMed Central
PMCID
4812640
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
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31 March 2020
James A Hoxie
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4
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James A Hoxie
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Europe PubMed Central
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4812640
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31 March 2020
author name string
Haitao Guo
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2
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4812640
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
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31 March 2020
Jerry Jeffrey
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3
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4812640
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31 March 2020
publication date
29 March 2016
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Europe PubMed Central
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4812640
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31 March 2020
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Retrovirology
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4812640
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31 March 2020
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13
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4812640
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31 March 2020
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22
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Europe PubMed Central
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4812640
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
exact match
https://scigraph.springernature.com/pub.10.1186/s12977-016-0255-z
0 references
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HIV-1 Env and Nef Cooperatively Contribute to Plasmacytoid Dendritic Cell Activation via CD4-Dependent Mechanisms
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Viral factors in non-progression
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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
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Critical roles for Akt kinase in controlling HIV envelope-mediated depletion of CD4 T cells
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HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activity
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Type I interferon contributes to CD4+ T cell depletion induced by infection with HIV-1 in the human thymus
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Mechanisms of HIV-associated lymphocyte apoptosis: 2010
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Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue
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Chemokine coreceptor signaling in HIV-1 infection and pathogenesis
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Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism
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FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo
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V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies
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HIV-1 infection and pathogenesis in a novel humanized mouse model
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The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1.
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Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus
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Differential pathogenesis of primary CCR5-using human immunodeficiency virus type 1 isolates in ex vivo human lymphoid tissue
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HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation
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Apoptosis of uninfected cells induced by HIV envelope glycoproteins
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Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes.
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The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
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5 September 2018
Early activation of mitogen-activated protein kinase kinase, extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and c-Jun N-terminal kinase in response to binding of simian immunodeficiency virus to Jurkat T cells expressin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27026376
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK
1 reference
stated in
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reference URL
https://pubmed.ncbi.nlm.nih.gov/27026376
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27026376
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/S12977-016-0255-Z
1 reference
stated in
Europe PubMed Central
PMCID
4812640
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
Dimensions Publication ID
1011476443
0 references
PMCID
4812640
1 reference
stated in
Europe PubMed Central
PMCID
4812640
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
PubMed ID
27026376
1 reference
stated in
Europe PubMed Central
PMCID
4812640
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27026376%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
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