(Q36974683)

English

Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism

scientific article published on 17 September 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

17 August 2017

Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism (English)

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Europe PubMed Central

PMC publication ID

17 August 2017

11

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Pablo Tebas

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17 August 2017

Karuppiah Muthumani

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Karuppiah Muthumani

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David B. Weiner

13

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David B Weiner

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17 August 2017

author name string

Andrew Y Choo

2

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17 August 2017

Devon J Shedlock

3

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Europe PubMed Central

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17 August 2017

Dominick J Laddy

4

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17 August 2017

Senthil G Sundaram

5

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Europe PubMed Central

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17 August 2017

Lauren Hirao

6

1 reference

Europe PubMed Central

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17 August 2017

Ling Wu

7

1 reference

Europe PubMed Central

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17 August 2017

Khanh P Thieu

8

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Europe PubMed Central

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17 August 2017

Christopher W Chung

9

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17 August 2017

Karthikbabu M Lankaraman

10

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17 August 2017

Guido Silvestri

12

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17 August 2017

language of work or name

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publication date

17 September 2008

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Europe PubMed Central

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17 August 2017

Journal of Virology

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17 August 2017

82

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Europe PubMed Central

PMC publication ID

17 August 2017

23

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Europe PubMed Central

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17 August 2017

11536-11544

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Europe PubMed Central

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17 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2583658/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques

1 reference

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PD-1 and its ligands in tolerance and immunity

1 reference

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Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination

1 reference

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Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

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Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade

1 reference

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PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

1 reference

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29 September 2017

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

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29 September 2017

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

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29 September 2017

Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways

1 reference

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29 September 2017

The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1

1 reference

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29 September 2017

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

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29 September 2017

HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation

1 reference

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29 September 2017

HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound

1 reference

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29 September 2017

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 reference

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29 September 2017

Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions

1 reference

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29 September 2017

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

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Pathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated Nef

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580.

1 reference

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29 September 2017

In vivo pathogenesis of a human immunodeficiency virus type 1 reporter virus

1 reference

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29 September 2017

Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells

1 reference

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29 September 2017

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583658

29 September 2017

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

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29 September 2017

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

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29 September 2017

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1 reference

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29 September 2017

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

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Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

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27 June 2018

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583658

4 September 2018

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583658

4 September 2018

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583658

4 September 2018

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18799583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18799583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18799583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00485-08

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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