(Q36745738)

English

Opioid peptidomimetics: leads for the design of bioavailable mixed efficacy μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands

scientific article published on 27 February 2013

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

Opioid peptidomimetics: leads for the design of bioavailable mixed efficacy μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands (English)

1 reference

Europe PubMed Central

16 August 2017

0 references

Aubrie A Harland

object named as

Aubrie A Harland

3

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object named as

Larisa Yeomans

2

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author name string

Henry I Mosberg

1

1 reference

Europe PubMed Central

16 August 2017

Aaron M Bender

4

1 reference

Europe PubMed Central

16 August 2017

Katarzyna Sobczyk-Kojiro

5

1 reference

Europe PubMed Central

16 August 2017

Jessica P Anand

6

1 reference

Europe PubMed Central

16 August 2017

Mary J Clark

7

1 reference

Europe PubMed Central

16 August 2017

Emily M Jutkiewicz

8

1 reference

Europe PubMed Central

16 August 2017

John R Traynor

9

1 reference

Europe PubMed Central

16 August 2017

language of work or name

0 references

publication date

27 February 2013

1 reference

Europe PubMed Central

16 August 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

16 August 2017

56

1 reference

Europe PubMed Central

16 August 2017

5

1 reference

Europe PubMed Central

16 August 2017

2139-2149

1 reference

Europe PubMed Central

16 August 2017

14-Alkoxy- and 14-acyloxypyridomorphinans: μ agonist/δ antagonist opioid analgesics with diminished tolerance and dependence side effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Modulation of opioid receptor ligand affinity and efficacy using active and inactive state receptor models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

μ-Opioid receptor coupling to Gα(o) plays an important role in opioid antinociception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Development of potent μ and δ opioid agonists with high lipophilicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

In vivo characterization of MMP-2200, a mixed δ/μ opioid agonist, in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Opioid-dopamine interactions: implications for substance use disorders and their treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Evolution of the Bifunctional Lead μ Agonist / δ Antagonist Containing the Dmt-Tic Opioid Pharmacophore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Simultaneous targeting of multiple opioid receptors: a strategy to improve side-effect profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Designing multiple ligands - medicinal chemistry strategies and challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Cell-penetrating peptides: mechanisms and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Designed multiple ligands. An emerging drug discovery paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Development of neuropeptide drugs that cross the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

From magic bullets to designed multiple ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Antinociceptive profile of biphalin, a dimeric enkephalin analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

29 September 2017

Differential binding properties of oripavines at cloned mu- and delta-opioid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

28 June 2018

Modulation of the potency and efficacy of mu-mediated antinociception by delta agonists in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

28 June 2018

Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

Effects of mixed-action kappa/mu opioids on cocaine self-administration and cocaine discrimination by rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

Design of a high affinity peptidomimetic opioid agonist from peptide pharmacophore models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

Attenuation of morphine tolerance and dependence with the highly selective delta-opioid receptor antagonist TIPP[psi].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618660

5 September 2018

Differential effects of naltrindole on morphine-induced tolerance and physical dependence in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23419026

12 December 2020

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Identifiers

10.1021/JM400050Y

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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