(Q36755458)

English

Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors

scientific article published on 20 March 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Changxue Lu

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Mark C Willingham

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Fumihiko Furuya

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Sheue-Yann Cheng

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

20 March 2008

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

149

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

3339-3345

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention

1 reference

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29 September 2017

Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

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29 September 2017

Growth arrest of thyrotropic tumors by thyroid hormone is correlated with novel changes in Wnt-10A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer

1 reference

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29 September 2017

Morphologic changes associated with thyrotrophin-secreting pituitary tumors.

1 reference

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29 September 2017

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

1 reference

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29 September 2017

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

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29 September 2017

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Thyrotropin-secreting pituitary adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Octreotide therapy for thyroid-stimulating hormone-secreting pituitary adenomas. A follow-up of 52 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

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29 September 2017

Signal transduction by receptors with tyrosine kinase activity

1 reference

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29 September 2017

Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

PI3K: downstream AKTion blocks apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Thyrotropin-secreting pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

29 September 2017

Central hyperthyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

28 June 2018

The PI3K inhibitor arsenal: choose your weapon!

1 reference

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5 September 2018

The proliferative status of thyrotropes is dependent on modulation of specific cell cycle regulators by thyroid hormone.

1 reference

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5 September 2018

Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

5 September 2018

Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453100

5 September 2018

AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18356276

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early gene expression changes preceding thyroid hormone-induced involution of a thyrotrope tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18356276

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of thyrotropin-secreting pituitary adenomas to a long-acting somatostatin analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18356276

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin-producing pituitary adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18356276

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2007-1696

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

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