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English
Roles and mechanisms of action of the Nrf2 transcription factor in skin morphogenesis, wound repair and skin cancer.
scientific article published on 23 March 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
review article
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stated in
Europe PubMed Central
title
Roles and mechanisms of action of the Nrf2 transcription factor in skin morphogenesis, wound repair and skin cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
main subject
morphogenesis
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inferred from title
author
Ulrich auf dem Keller
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
author name string
Beyer TA
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Braun S
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Schäfer M
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Werner S
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
publication date
23 March 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
published in
Cell Death & Differentiation
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Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
issue
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
page(s)
1250-1254
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402133
0 references
cites work
Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nrf1 is critical for redox balance and survival of liver cells during development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Utility of siRNA against Keap1 as a strategy to stimulate a cancer chemopreventive phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low and high dose UVB regulation of transcription factor NF-E2-related factor 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: protective role in UVA-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402133
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4402133
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
PubMed publication ID
17380153
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17380153
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17380153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
ResearchGate publication ID
6427493
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