(Q36777326)

16 August 2017

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title

TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes (English)

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16 August 2017

author

Anne-Lise Børresen-Dale

series ordinal

3

object named as

Borresen-Dale AL

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16 August 2017

4

Hainaut P

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16 August 2017

Petitjean A

1

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16 August 2017

Achatz MI

series ordinal

2

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16 August 2017

Olivier M

series ordinal

5

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16 August 2017

language of work or name

English

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publication date

1 April 2007

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16 August 2017

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16 August 2017

volume

26

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16 August 2017

issue

15

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16 August 2017

page(s)

2157-2165

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210302

16 August 2017

exact match

0 references

cites work

The TP53 mutation, R337H, is associated with Li-Fraumeni and Li-Fraumeni-like syndromes in Brazilian families.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Is p53 polymorphism maintained by natural selection?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Screening for TP53 rearrangements in families with the Li-Fraumeni syndrome reveals a complete deletion of the TP53 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

The combination of p53 mutation and neu/erbB-2 amplification is associated with poor survival in node-negative breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Single-nucleotide polymorphisms in the p53 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 polymorphism and risk of cervical cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Two germ line polymorphisms of the tumour suppressor gene p53 may influence the biology of chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 codon 72 polymorphism and cervical neoplasia: a meta-analysis review

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Arrayed primer extension resequencing of mutations in the TP53 tumor suppressor gene: comparison with denaturing HPLC and direct sequencing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

A nucleotide substitution model with nearest-neighbour interactions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

TP53 mutation, allelism and survival in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

The IARC TP53 database: new online mutation analysis and recommendations to users

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 polymorphic variants at codon 72 exert different effects on cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

TP53 and P21 polymorphisms: response to cisplatinum/paclitaxel-based chemotherapy in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Retention of the arginine allele in codon 72 of the p53 gene correlates with poor apoptosis in head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Trp53-dependent DNA-repair is affected by the codon 72 polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Two polymorphic variants of wild-type p53 differ biochemically and biologically

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 polymorphic variants at codon 72 and the outcome of therapy in randomized breast cancer patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

p53 Codon 72 polymorphism predicts the pathologic response to neoadjuvant chemotherapy in patients with breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210302

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210302

1 reference

16 August 2017

1 reference