(Q36786614)

English

Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.

scientific article published on 14 June 2011

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scholarly article

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4 February 2020

Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673231%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

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4 February 2020

Christopher Kevil

6

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4 February 2020

Arlan G. Richardson

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Arlan Richardson

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4 February 2020

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Jennifer A Wittwer

1

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4 February 2020

Delira Robbins

2

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4 February 2020

Fei Wang

3

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4 February 2020

Sarah Codarin

4

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4 February 2020

Ting-Ting Huang

7

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4 February 2020

Yunfeng Zhao

10

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4 February 2020

Holly Van Remmen

8

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4 February 2020

publication date

14 June 2011

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4 February 2020

Cancer Prevention Research

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673231%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

4

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4 February 2020

9

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4 February 2020

1476-1484

1 reference

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4 February 2020

Regulation of cancer cell metabolism

1 reference

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29 September 2017

Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells

1 reference

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29 September 2017

Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

1 reference

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29 September 2017

The Chemopreventive Effects of Protandim: Modulation of p53 Mitochondrial Translocation and Apoptosis during Skin Carcinogenesis

1 reference

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29 September 2017

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells

1 reference

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29 September 2017

The clinicopathological and prognostic relevance of pyruvate kinase M2 and pAkt expression in breast cancer.

1 reference

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29 September 2017

Circulating tumor M2 pyruvate kinase and thymidine kinase 1 are potential predictors for disease recurrence in renal cell carcinoma after nephrectomy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice

1 reference

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29 September 2017

The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Identification of small molecule inhibitors of pyruvate kinase M2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Brick by brick: metabolism and tumor cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis

1 reference

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29 September 2017

Significance of the glycolytic pathway and glycolysis related-genes in tumorigenesis of human colorectal cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Energy metabolism in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Pyruvate kinase type M2 and its role in tumor growth and spreading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Why do cancers have high aerobic glycolysis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

On the Origin of Cancer Cells

1 reference

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29 September 2017

Detection of the content and activity of the transcription factor AP-1 in a multistage skin carcinogenesis model.

1 reference

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29 September 2017

Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7.

1 reference

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29 September 2017

Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Immunohistological demonstration of the same type of pyruvate kinase isoenzyme (M2-Pk) in tumors of chicken and rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4827450

29 September 2017

Expression of hypoxia-inducible genes in tumor cells

1 reference

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27 June 2018

The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy

1 reference

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27 June 2018

Crystallization, characterization and metabolic regulation of two types of pyruvate kinase isolated from rat tissues

1 reference

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27 June 2018

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters.

1 reference

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Tumor-specific correlation of tumor M2 pyruvate kinase in pre-invasive, invasive and recurrent cervical cancer.

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The Warburg Effect returns to the cancer stage

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New roles for pyruvate kinase M2: working out the Warburg effect

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Tamoxifen protects against acute tumor necrosis factor alpha-induced cardiac injury via improving mitochondrial functions.

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Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine-supplemented diet.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21673231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP- and fructose 1,6-bisphosphate-activated pyruvate kinases from Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of M1 and M2 isozymes pyruvate kinase from human tissues with phospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistologic photometric quantification of pyruvate kinase content of rat tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1940-6207.CAPR-11-0028

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673231%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673231%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21673231%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

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