(Q36794020)

16 August 2017

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title

JNK pathway: diseases and therapeutic potential (English)

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16 August 2017

Jie Cui

1

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16 August 2017

Ming Zhang

series ordinal

2

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16 August 2017

Yong-Qing Zhang

series ordinal

3

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16 August 2017

Zhi-Heng Xu

series ordinal

4

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16 August 2017

1 May 2007

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Acta Pharmacologica Sinica

16 August 2017

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16 August 2017

28

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16 August 2017

5

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16 August 2017

601-608

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https://scigraph.springernature.com/pub.10.1111/j.1745-7254.2007.00579.x

16 August 2017

0 references

cites work

Signal transduction by the JNK group of MAP kinases

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

The JNK signal transduction pathway

21 January 2018

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Modulation of the JNK pathway in liver affects insulin resistance status

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Targeting JNK for therapeutic benefit: from junk to gold?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

From receptors to stress-activated MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Mitogen-activated protein kinase kinase 7 is activated during low potassium-induced apoptosis in rat cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

A cytoplasmic inhibitor of the JNK signal transduction pathway

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Transcription factor ATF2 regulation by the JNK signal transduction pathway

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Signaling mechanisms underlying Abeta toxicity: potential therapeutic targets for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

A critical role of neural-specific JNK3 for ischemic apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Repression of phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Knock-down of POSH expression is neuroprotective through down-regulating activation of the MLK3-MKK4-JNK pathway following cerebral ischaemia in the rat hippocampal CA1 subfield

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

JNK: a new therapeutic target for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Neurotrophic 3,9-bis[(alkylthio)methyl]-and-bis(alkoxymethyl)-K-252a derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Control of death receptor and mitochondrial-dependent apoptosis by c-Jun N-terminal kinase in hippocampal CA1 neurones following global transient ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

D-JNKI1, a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

Intracellular Stress Signaling Pathways Activated During Human Islet Preparation and Following Acute Cytokine Exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00579.X

K-252a, a potent inhibitor of protein kinase C from microbial origin

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.39.1059

Identifiers

DOI

10.1111/J.1745-7254.2007.00579.X

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference