(Q35736273)

10 August 2017

title

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease (English)

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10 August 2017

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6

Serge Przedborski

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10 August 2017

Stéphane Hunot

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Miquel Vila

object named as

Miquel Vila

2

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Richard Flavell

8

object named as

Richard A Flavell

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10 August 2017

4

Roger J Davis

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10 August 2017

Peter Teismann

3

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10 August 2017

Etienne C Hirsch

5

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10 August 2017

Pasko Rakic

7

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10 August 2017

language of work or name

English

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publication date

2 January 2004

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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10 August 2017

volume

101

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10 August 2017

issue

2

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10 August 2017

page(s)

665-670

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Parkinson's disease: mechanisms and models

10 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

The c-Jun N-terminal kinases in cerebral microglia: immunological functions in the brain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

The role of glial cells in Parkinson's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Fluid shear stress-induced cyclooxygenase-2 expression is mediated by C/EBP beta, cAMP-response element-binding protein, and AP-1 in osteoblastic MC3T3-E1 cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Redundancy in the signaling pathways and promoter elements regulating cyclooxygenase-2 gene expression in endotoxin-treated macrophage/monocytic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Signal transduction by the JNK group of MAP kinases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Regional and strain-specific gene expression mapping in the adult mouse brain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Cyclooxygenases: structural, cellular, and molecular biology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Mechanisms of excitotoxicity in neurologic diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Etiology and pathogenesis of Parkinson's disease

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

Indomethacin protects against neurodegeneration caused by MPTP intoxication in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327205

Genetics of Parkinson's disease and biochemical studies of implicated gene products: Commentary

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307453101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0307453101

1 reference

10 August 2017

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10 August 2017

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