(Q36794851)

English

The pharmacokinetics of antiepileptic drugs in rats: consequences for maintaining effective drug levels during prolonged drug administration in rat models of epilepsy

scientific article published on 18 April 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

1 reference

Europe PubMed Central

The pharmacokinetics of antiepileptic drugs in rats: consequences for maintaining effective drug levels during prolonged drug administration in rat models of epilepsy (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Wolfgang Löscher

1

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

18 April 2007

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

48

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

1245-1258

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

Comparative pharmacokinetics and metabolism of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit and dog.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Influence of administration vehicles and drug formulations on the pharmacokinetic profile of lamotrigine in rats.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Relationship between plasma and brain levels and the anticonvulsant effect of lamotrigine in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Blood and cerebrospinal fluid pharmacokinetics of the novel anticonvulsant levetiracetam (ucb L059) in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Sex differences in the anticonvulsant efficacy of phenytoin in amygdala-kindled rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Methodology for pharmacokinetic/pharmacodynamic data analysis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Use of chronic epilepsy models in antiepileptic drug discovery: the effect of topiramate on spontaneous motor seizures in rats with kainate-induced epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Chronic elevation of brain GABA levels beginning two days after status epilepticus does not prevent epileptogenesis in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Gender differences in the pharmacodynamics of barbiturates in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Kindling Increases the Sensitivity of Rats to Adverse Effects of Certain Antiepileptic Drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Pharmacokinetics of phenobarbital and propylhexedrine after administration of barbexaclone in the mouse

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Role of rat strain in the differential sensitivity to pharmaceutical agents and naturally occurring substances

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Single-dose pharmacokinetics and anticonvulsant efficacy of primidone in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Experimental methods of ethanol administration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Comparison of the anticonvulsant efficacy of primidone and phenobarbital during chronic treatment of amygdala-kindled rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Comparison of Anticonvulsant Efficacy of Valproate During Prolonged Treatment with One and Three Daily Doses or Continuous (“Controlled Release”) Administration in a Model of Generalized Seizures in Rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Drug resistance in brain diseases and the role of drug efflux transporters.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

New horizons in the development of antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

New Horizons in the development of antiepileptic drugs: Innovative strategies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Development of tolerance to the anticonvulsant effect of diazepam in amygdala-kindled rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Teratogenic valproic acid concentrations: infusion by implanted minipumps vs conventional injection regimen in the mouse

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Pharmacokinetics of valproic acid and metabolites in mouse plasma and brain following constant-rate application of the drug and its unsaturated metabolite with an osmotic delivery system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Therapeutic drug monitoring of old and newer anti-epileptic drugs.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Effects of vigabatrin treatment on status epilepticus-induced neuronal damage and mossy fiber sprouting in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Development of tolerance to the anticonvulsant effect of vigabatrin in amygdala-kindled rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Current evidence indicates that antiepileptic drugs are anti-ictal, not antiepileptic

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Biochemical basis of sex differences in drug metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Effects of sodium valproate on corticotropin-releasing factor systems in rat brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Antiepileptogenic agents: how close are we?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

INTERNAL MEDICINE IN THE 21ST CENTURY: Controlled drug delivery: therapeutic and pharmacological aspects

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

Comparison of serum, cerebrospinal fluid and brain extracellular fluid pharmacokinetics of lamotrigine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2007.01093.X

21 January 2018

The pharmacokinetic inter-relationship of tiagabine in blood, cerebrospinal fluid and brain extracellular fluid (frontal cortex and hippocampus).

1 reference

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21 January 2018

Identifiers

10.1111/J.1528-1167.2007.01093.X

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

ResearchGate publication ID

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