(Q36795534)

16 August 2017

Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner (English)

1 reference

16 August 2017

4

H Miao

1 reference

16 August 2017

S He

1

1 reference

16 August 2017

B Malik

2

1 reference

16 August 2017

D Borkin

3

1 reference

16 August 2017

S Shukla

5

1 reference

16 August 2017

K Kempinska

6

1 reference

16 August 2017

T Purohit

7

1 reference

16 August 2017

J Wang

8

1 reference

16 August 2017

L Chen

9

1 reference

16 August 2017

B Parkin

10

1 reference

16 August 2017

S N Malek

11

1 reference

16 August 2017

G Danet-Desnoyers

12

1 reference

16 August 2017

A G Muntean

13

1 reference

16 August 2017

T Cierpicki

14

1 reference

16 August 2017

J Grembecka

15

1 reference

16 August 2017

18 June 2015

1 reference

16 August 2017

1 reference

16 August 2017

30

1 reference

16 August 2017

2

1 reference

16 August 2017

508-513

1 reference

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Disordered epigenetic regulation in MLL-related leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Mechanisms of leukemogenesis by MLL fusion proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

The molecular biology of mixed lineage leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830728

Chromosomal Aberration of the 11q23 Locus in Acute Leukemia and Frequency of MLL Gene Translocation Results in 378 Adult Patients

27 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2015.144

Chromosomal aberration of the 11q23 locus in acute leukemia and frequency of MLL gene translocation: results in 378 adult patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26084867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LEU.2015.144

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

26084867

1 reference