(Q40637557)

22 September 2017

title

Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias (English)

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22 September 2017

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Chi Wai So

1

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22 September 2017

Min Lin

2

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22 September 2017

Paul M Ayton

3

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22 September 2017

Everett H Chen

4

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22 September 2017

Michael L Cleary

5

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22 September 2017

publication date

1 August 2003

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22 September 2017

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22 September 2017

volume

4

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22 September 2017

issue

2

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22 September 2017

page(s)

99-110

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Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Oncogenic conversion of transcription factors by chromosomal translocations

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Parallel dimers and anti-parallel tetramers formed by epidermal growth factor receptor pathway substrate clone 15.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Essential role for the dimerization domain of NuMA-RARalpha in its oncogenic activities and localization to NuMA sites within the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

PCIF1, a novel human WW domain-containing protein, interacts with the phosphorylated RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

eps15, A Novel Tyrosine Kinase Substrate, Exhibits Transforming Activity

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

gas7: A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14).

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Oncogenic transcription factors in the human acute leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

HOX and non-HOX homeobox genes in leukemic hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Chromosomal translocations in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Epidermal growth factor pathway substrate 15, Eps15.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Transcription factor fusions in acute leukemia: variations on a theme.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Self-fusion of the ALL1 gene. A new genetic mechanism for acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Association of the growth-arrest-specific protein Gas7 with F-actin induces reorganization of microfilaments and promotes membrane outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Common mechanism for oncogenic activation of MLL by forkhead family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The impact of differential binding of wild-type RARalpha, PML-, PLZF- and NPM-RARalpha fusion proteins towards transcriptional co-activator, RIP-140, on retinoic acid responses in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21).

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Eps15 is constitutively oligomerized due to homophilic interaction of its coiled-coil region

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Altered Hox expression and segmental identity in Mll-mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900188-0

7 January 2021

10.1016/S1535-6108(03)00188-0

Identifiers

DOI

1 reference

22 September 2017

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