(Q34658565)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

review article

1 reference

title

Transcription factor fusions in acute leukemia: variations on a theme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

Piernicola Boccuni

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Jorg Cammenga

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Stephen D Nimer

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 May 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

3422-3444

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205315

9 November 2019

exact match

0 references

cites work

Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

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7 January 2021

The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates

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7 January 2021

Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO.

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7 January 2021

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

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7 January 2021

Common themes in the pathogenesis of acute myeloid leukemia

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7 January 2021

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

1 reference

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7 January 2021

Molecular detection of t(8;21)/AML1-ETO in AML M1/M2: correlation with cytogenetics, morphology and immunophenotype

1 reference

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7 January 2021

AT-hook motifs identified in a wide variety of DNA-binding proteins

1 reference

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7 January 2021

The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia

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7 January 2021

Groucho-dependent and -independent repression activities of Runt domain proteins

1 reference

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7 January 2021

Mutational analysis of the murine granzyme B gene promoter in primary T cells and a T cell clone.

1 reference

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7 January 2021

Plzf regulates limb and axial skeletal patterning

1 reference

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7 January 2021

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila

1 reference

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7 January 2021

Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The mixed lineage leukemia (MLL) protein involved in 11q23 translocations contains a domain that binds cruciform DNA and scaffold attachment region (SAR) DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

1 reference

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7 January 2021

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation

1 reference

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7 January 2021

Recurrent granulocytic sarcoma. An unusual variation of acute myelogenous leukemia associated with 8;21 chromosomal translocation and blast expression of the neural cell adhesion molecule

1 reference

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7 January 2021

Gene targeting reveals a crucial role for MTG8 in the gut.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The core binding factor (CBF) alpha interaction domain and the smooth muscle myosin heavy chain (SMMHC) segment of CBFbeta-SMMHC are both required to slow cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Posttranslational modification of TEL and TEL/AML1 by SUMO-1 and cell-cycle-dependent assembly into nuclear bodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Determinants of specificity in TGF-beta signal transduction.

1 reference

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7 January 2021

Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Human AML1/MDS1/EVI1 fusion protein induces an acute myelogenous leukemia (AML) in mice: a model for human AML

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Transformation of hematopoietic cells by the Ski oncoprotein involves repression of retinoic acid receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Biology and therapy of secondary leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

p21(cip1) mRNA is controlled by endogenous transforming growth factor-beta1 in quiescent human hematopoietic stem/progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Transgenic expression of PML/RARalpha impairs myelopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Signal transduction by transforming growth factor-β: A cooperative paradigm with extensive negative regulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Characterization of a cell-type-restricted negative regulatory activity of the human granulocyte-macrophage colony-stimulating factor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Infant acute lymphoblastic leukaemia with t(11; 19)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Histone acetylation in chromatin structure and transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The function of PML in p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

RETRACTED: The leukemic core binding factor beta-smooth muscle myosin heavy chain (CBF beta-SMMHC) chimeric protein requires both CBF beta and myosin heavy chain domains for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Two critical hits for promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Multiple regions of ETO cooperate in transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Acute myeloblastic leukaemia and t(8;21) translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Inhibition of the transforming growth factor beta 1 signaling pathway by the AML1/ETO leukemia-associated fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

c-Myc is a critical target for c/EBPalpha in granulopoiesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Prognostic importance of cytogenetic subgroups in de novo pediatric acute nonlymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Cytoplasmic sequestration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor alpha (CBFalpha) subunit by the leukemia-related PEBP2/CBFbeta-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

AML1, the target of chromosomal rearrangements in human leukemia, regulates the expression of human complement receptor type 1 (CR1) gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The AML1/ETO fusion protein activates transcription of BCL-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Acetylation: a regulatory modification to rival phosphorylation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Frequency of CBF beta/MYH11 fusion transcripts in patients entered into the U.K. MRC AML trials. The MRC Adult Leukaemia Working Party

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials. MRC Adult Leukaemia Working Party

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Genomic and proteomic analysis of the myeloid differentiation program

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Frequency of RAS and p53 mutations in acute promyelocytic leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Oncogenic transcription factors in the human acute leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Association with the nuclear matrix and interaction with Groucho and RUNX proteins regulate the transcription repression activity of the basic helix loop helix factor Hes1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Potential role for wild-type p53 in leukemias with MLL gene translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Clinical importance of cytogenetics in acute myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Stable overexpression of PML alters regulation of cell cycle progression in HeLa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

11p15 translocations involving the NUP98 gene in childhood therapy-related acute myeloid leukemia/myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Oncogenes and tumor suppressors in the molecular pathogenesis of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A phorbol ester response element within the human T-cell receptor beta-chain enhancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Chromosomal translocations in human cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Role of promyelocytic leukemia (PML) protein in tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Stem cells, cancer, and cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

RTK mutations and human syndromes: when good receptors turn bad

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

1 reference

7 January 2021

Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): a report from the Children's Cancer Group.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Pure human hematopoietic progenitors: direct inhibitory effect of transforming growth factors-beta 1 and -beta 2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Chromosome abnormalities and MLL rearrangements in acute myeloid leukemia of infants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

C/EBPalpha inhibits cell growth via direct repression of E2F-DP-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

All-trans retinoic acid significantly increases 5-year survival in patients with acute promyelocytic leukemia: long-term follow-up of the New York study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

MDS1/EVI1 enhances TGF-beta1 signaling and strengthens its growth-inhibitory effect but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

8;21 translocation in acute granulocytic leukaemia: cytological, cytochemical and clinical features

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

PML is essential for multiple apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Pathogenesis and management of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Cooperative binding of Ets-1 and core binding factor to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

AML and Ets proteins regulate the I alpha1 germ-line promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Cloning and characterization of human karyopherin beta3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Transcriptional regulation of the transforming growth factor-beta -inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB, and AML family members.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

The transcriptional role of PML and the nuclear body

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205315

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205315

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032780%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

0 references

1 reference