(Q36804540)

16 August 2017

Human embryonic stem cells: the battle between self-renewal and differentiation (English)

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human embryonic stem cell

16 August 2017

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2

Nissim Benvenisty

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16 August 2017

Henia Darr

1

1 reference

16 August 2017

1 May 2006

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16 August 2017

Regenerative Medicine

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16 August 2017

1

1 reference

16 August 2017

317-325

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16 August 2017

3

1 reference

Embryonic stem cell lines derived from human blastocysts

16 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Therapeutic applications of embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Self-renewal of teratocarcinoma and embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Diverse mechanisms regulate stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Feeder-free growth of undifferentiated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Maintenance of pluripotency in human embryonic stem cells is STAT3 independent

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Basic fibroblast growth factor activates ERK and induces c-fos in human embryonic stem cell line MizhES1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Feeder layer- and serum-free culture of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Derivation of human embryonic stem cells in defined conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

High-efficiency RNA interference in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Multipotent cell lineages in early mouse development depend on SOX2 function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

SOX2 functions to maintain neural progenitor identity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Differences between human and mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Transcriptional regulation of nanog by OCT4 and SOX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Differentiation of embryonic stem cells is induced by GATA factors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Core transcriptional regulatory circuitry in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Expression of Nanog gene promotes NIH3T3 cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Culture and characterization of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

BMP4 initiates human embryonic stem cell differentiation to trophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

Oct-3/4 is a dose-dependent oncogenic fate determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17460751.1.3.317

21 January 2018

Identifiers

DOI

10.2217/17460751.1.3.317

1 reference

16 August 2017

1 reference

PubMed ID

17465785