(Q36806108)

16 August 2017

title

Mutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3. (English)

1 reference

16 August 2017

5

1 reference

16 August 2017

Ming Cheng

1

1 reference

16 August 2017

Shen-Yun Foo

2

1 reference

16 August 2017

Min-Long Shi

3

1 reference

16 August 2017

Ren-Hong Tang

4

1 reference

16 August 2017

S K Alex Law

6

1 reference

16 August 2017

Suet-Mien Tan

7

1 reference

16 August 2017

language of work or name

English

0 references

publication date

26 April 2007

1 reference

Journal of Biological Chemistry

16 August 2017

published in

1 reference

16 August 2017

volume

282

1 reference

16 August 2017

issue

25

1 reference

16 August 2017

page(s)

18225-18232

1 reference

Integrins: bidirectional, allosteric signaling machines

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Integrin structure, allostery, and bidirectional signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Structural basis of integrin regulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Two conformations of the integrin A-domain (I-domain): a pathway for activation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Stabilizing the integrin alpha M inserted domain in alternative conformations with a range of engineered disulfide bonds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Genetic analysis of integrin function in man: LAD-1 and other syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Structural basis of collagen recognition by integrin alpha2beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Epitope mapping of antibodies to the C-terminal region of the integrin beta 2 subunit reveals regions that become exposed upon receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Molecular evolution of integrins: genes encoding integrin beta subunits from a coral and a sponge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

A novel adaptation of the integrin PSI domain revealed from its crystal structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Integrin structures and conformational signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

KIM127, an antibody that promotes adhesion, maps to a region of CD18 that includes cysteine-rich repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701386200

21 January 2018

Identifiers

DOI

10.1074/JBC.M701386200

1 reference

16 August 2017

1 reference