(Q36822431)

16 August 2017

1 reference

title

Oxidative stress and steroid resistance in asthma and COPD: pharmacological manipulation of HDAC-2 as a therapeutic strategy (English)

1 reference

chronic obstructive pulmonary disease

16 August 2017

main subject

1 reference

1 reference

2

Kazuhiro Ito

1 reference

16 August 2017

3

Ian M Adcock

1 reference

16 August 2017

John A Marwick

1

1 reference

16 August 2017

Paul A Kirkham

series ordinal

4

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 June 2007

1 reference

Expert Opinion on Therapeutic Targets

16 August 2017

published in

1 reference

16 August 2017

volume

11

1 reference

16 August 2017

issue

6

1 reference

16 August 2017

page(s)

745-755

1 reference

Corticosteroid-insensitive asthma: molecular mechanisms.

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials

21 January 2018

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The nature of small-airway obstruction in chronic obstructive pulmonary disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Oxidant-mediated activation of mitogen-activated protein kinases and nuclear transcription factors in the cardiovascular system: a brief overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Oxidants and signaling by mitogen-activated protein kinases in lung epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Free-radical chemistry of cigarette smoke and its toxicological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

The effects of outdoor air pollution and tobacco smoke on asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Redox and oxidant-mediated regulation of apoptosis signaling pathways: immuno-pharmaco-redox conception of oxidative siege versus cell death commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Acute effects of cigarette smoke on inflammation and oxidative stress: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Oxidative stress and regulation of glutathione in lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Mediators of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Cytokines as targets in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Role of oxidants/antioxidants in smoking-induced lung diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Steroid resistance in asthma: a major problem requiring novel solutions or a non-issue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Effects of glucocorticoids on gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone acetylation in chromatin structure and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Signaling to chromatin through histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Preparing the target for the bullet

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

It takes a PHD to read the histone code

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

What's up and down with histone deacetylation and transcription?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylases: complex transducers of nuclear signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

DNA associated with hyperacetylated histone is preferentially digested by DNase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylase activity is required for full transcriptional repression by mSin3A

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

CoREST is an integral component of the CoREST- human histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylases, transcriptional control, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylases: silencers for hire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Expression and activity of histone deacetylases in human asthmatic airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Protein-bound acrolein: potential markers for oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Biological selectivity and functional aspects of protein tyrosine nitration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Subcellular localization of glucocorticoid receptor protein in the human kidney glomerulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Ligand-selective targeting of the glucocorticoid receptor to nuclear subdomains is associated with decreased receptor mobility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Mechanisms involved in the side effects of glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Combinatorial roles of nuclear receptors in inflammation and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Coregulator codes of transcriptional regulation by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Glucocorticoid pathways in chronic obstructive pulmonary disease therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Regulation of histone deacetylase 2 by protein kinase CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

An expression screen reveals modulators of class II histone deacetylase phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

In vivo resistance to corticosteroids in bronchial asthma is associated with enhanced phosyphorylation of JUN N-terminal kinase and failure of prednisolone to inhibit JUN N-terminal kinase phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

How corticosteroids control inflammation: Quintiles Prize Lecture 2005

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Comparison of tiotropium once daily, formoterol twice daily and both combined once daily in patients with COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Acetylation and deacetylation of non-histone proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Trichostatin A attenuates airway inflammation in mouse asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Histone deacetylase inhibitors: latest developments, trends and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Peroxisome proliferator-activated receptor-gamma agonists as potential anti-inflammatory agents in asthma and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Peroxisome proliferator-activated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

Increased expression of histone deacetylase 2 is found in human gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.6.745

10.1517/14728222.11.6.745

21 January 2018

Identifiers

DOI

1 reference

release_ihmt4ylq4nakbkki3e4eqt2leq

16 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ihmt4ylq4nakbkki3e4eqt2leq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference