(Q36827306)

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The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

scientific article published on 6 March 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Stefan Pöhlmann

15

object named as

Stefan Pöhlmann

0 references

Florian Wrensch

object named as

Florian Wrensch

4

0 references

object named as

Graham Simmons

13

0 references

Christian Drosten

10

object named as

Christian Drosten

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

11

object named as

Ulf Dittmer

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Stephanie Stanelle-Bertram

2

object named as

Stephanie Bertram

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Stefanie Gierer

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Franziska Kaup

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Adeline Heurich

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Annika Krämer-Kühl

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Kathrin Welsch

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Michael Winkler

8

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Europe PubMed Central

PMC publication ID

16 August 2017

Benjamin Meyer

9

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Europe PubMed Central

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16 August 2017

Thomas von Hahn

12

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Europe PubMed Central

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16 August 2017

Heike Hofmann

14

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Europe PubMed Central

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16 August 2017

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publication date

6 March 2013

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Europe PubMed Central

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16 August 2017

Journal of Virology

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Europe PubMed Central

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16 August 2017

87

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Europe PubMed Central

PMC publication ID

16 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

5502-5511

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Ecology of zoonoses: natural and unnatural histories

1 reference

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29 September 2017

Development of novel entry inhibitors targeting emerging viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Mechanisms of coronavirus cell entry mediated by the viral spike protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Protease-mediated entry via the endosome of human coronavirus 229E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Amino acid substitutions in the S2 subunit of mouse hepatitis virus variant V51 encode determinants of host range expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

The novel human coronaviruses NL63 and HKU1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Virus membrane-fusion proteins: more than one way to make a hairpin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Bats are natural reservoirs of SARS-like coronaviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Multiple organ infection and the pathogenesis of SARS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Persistent infection promotes cross-species transmissibility of mouse hepatitis virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Major receptor-binding and neutralization determinants are located within the same domain of the transmissible gastroenteritis virus (coronavirus) spike protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

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Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

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Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

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Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Human aminopeptidase N is a receptor for human coronavirus 229E

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3648152

29 September 2017

Contact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012.

1 reference

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Efficient multiplication of human metapneumovirus in Vero cells expressing the transmembrane serine protease TMPRSS2.

1 reference

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27 June 2018

Entry pathway of vesicular stomatitis virus into different host cells

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27 June 2018

The pH independence of mammalian retrovirus infection

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27 June 2018

A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC.

1 reference

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5 September 2018

Acute renal failure in patients with severe acute respiratory syndrome.

1 reference

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Severe acute respiratory syndrome-related diarrhea

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5 September 2018

Fatal severe acute respiratory syndrome is associated with multiorgan involvement by coronavirus

1 reference

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Infection of cultured intestinal epithelial cells with severe acute respiratory syndrome coronavirus

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Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice

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5 September 2018

Severe acute respiratory syndrome

1 reference

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Effects of a "new" human respiratory virus in volunteers

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00128-13

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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