(Q36830338)

English

miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN.

scientific article published on 20 April 2016

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN. (English)

1 reference

Europe PubMed Central

16 August 2017

author name string

Mengyang Zhao

1

1 reference

Europe PubMed Central

16 August 2017

Rongcheng Luo

2

1 reference

Europe PubMed Central

16 August 2017

Yiyi Liu

3

1 reference

Europe PubMed Central

16 August 2017

Linyuan Gao

4

1 reference

Europe PubMed Central

16 August 2017

Zhaojian Fu

5

1 reference

Europe PubMed Central

16 August 2017

Qiaofen Fu

6

1 reference

Europe PubMed Central

16 August 2017

Xiaojun Luo

7

1 reference

Europe PubMed Central

16 August 2017

Yiyu Chen

8

1 reference

Europe PubMed Central

16 August 2017

Xiaojie Deng

9

1 reference

Europe PubMed Central

16 August 2017

Zixi Liang

10

1 reference

Europe PubMed Central

16 August 2017

Xin Li

11

1 reference

Europe PubMed Central

16 August 2017

Chao Cheng

12

1 reference

Europe PubMed Central

16 August 2017

Zhen Liu

13

1 reference

Europe PubMed Central

16 August 2017

Weiyi Fang

14

1 reference

Europe PubMed Central

16 August 2017

publication date

20 April 2016

1 reference

Europe PubMed Central

16 August 2017

Nature Communications

1 reference

Europe PubMed Central

16 August 2017

7

1 reference

Europe PubMed Central

16 August 2017

11309

1 reference

Europe PubMed Central

16 August 2017

https://scigraph.springernature.com/pub.10.1038/ncomms11309

0 references

Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma

1 reference

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The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling

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Transforming growth factor-β promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway

1 reference

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EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN.

1 reference

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microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition.

1 reference

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PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling

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The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway

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Epithelial-mesenchymal transition is necessary for acquired resistance to cisplatin and increases the metastatic potential of nasopharyngeal carcinoma cells

1 reference

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29 September 2017

Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

1 reference

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Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency

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Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

1 reference

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MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma

1 reference

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29 September 2017

Roles for microRNAs in conferring robustness to biological processes

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EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

1 reference

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FOXO1 is a tumor suppressor in classical Hodgkin lymphoma.

1 reference

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Expression of FOXO1 is associated with GATA3 and Annexin-1 and predicts disease-free survival in breast cancer

1 reference

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MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1.

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microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network

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29 September 2017

Overproduction of cyclin D1 is dependent on activated mTORC1 signal in nasopharyngeal carcinoma: implication for therapy

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mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels.

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

1 reference

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29 September 2017

Silencing of LMP1 induces cell cycle arrest and enhances chemosensitivity through inhibition of AKT signaling pathway in EBV-positive nasopharyngeal carcinoma cells

1 reference

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29 September 2017

The enigmatic epidemiology of nasopharyngeal carcinoma

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29 September 2017

Tumour-related microRNAs functions in Caenorhabditis elegans.

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29 September 2017

Microarray RNA transcriptional profiling: part II. Analytical considerations and annotation

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29 September 2017

Nasopharyngeal carcinoma

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29 September 2017

Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

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FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma

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How microRNAs control cell division, differentiation and death

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29 September 2017

PI3K/Akt/mTOR pathway as a target for cancer therapy

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An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues

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Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

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29 September 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44.

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Platelet-activating factor receptor-mediated PI3K/AKT activation contributes to the malignant development of esophageal squamous cell carcinoma.

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Decreased miRNA-637 is an unfavorable prognosis marker and promotes glioma cell growth, migration and invasion via direct targeting Akt1.

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miR-508 sustains phosphoinositide signalling and promotes aggressive phenotype of oesophageal squamous cell carcinoma.

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5 September 2018

Overexpression of phospho-Akt correlates with phosphorylation of EGF receptor, FKHR and BAD in nasopharyngeal carcinoma

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based on heuristic

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Identifiers

10.1038/NCOMMS11309

1 reference

Europe PubMed Central

16 August 2017

2016NatCo...711309Z

0 references

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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