(Q36832193)

16 August 2017

A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts (English)

1 reference

16 August 2017

Carmine Settembre

2

0 references

Gérard Karsenty

object named as

Gerard Karsenty

8

0 references

Andrea Ballabio

object named as

Andrea Ballabio

7

0 references

author name string

Mathieu Ferron

1

1 reference

16 August 2017

Junko Shimazu

3

1 reference

16 August 2017

Julie Lacombe

4

1 reference

16 August 2017

Shigeaki Kato

5

1 reference

16 August 2017

David J Rawlings

6

1 reference

16 August 2017

18 April 2013

1 reference

16 August 2017

1 reference

16 August 2017

27

1 reference

16 August 2017

8

1 reference

16 August 2017

955-969

1 reference

describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3650231/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation

29 September 2017

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Comparative phosphoproteomic analysis of neonatal and adult murine brain

29 September 2017

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Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts

29 September 2017

1 reference

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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis

29 September 2017

1 reference

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MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

29 September 2017

1 reference

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A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

29 September 2017

1 reference

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Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans

29 September 2017

1 reference

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance

29 September 2017

1 reference

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Regulation of TFEB and V-ATPases by mTORC1.

29 September 2017

1 reference

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

29 September 2017

1 reference

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TFEB links autophagy to lysosomal biogenesis

29 September 2017

1 reference

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System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

29 September 2017

1 reference

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A tissue-specific atlas of mouse protein phosphorylation and expression

29 September 2017

1 reference

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Screening of protein kinase inhibitors identifies PKC inhibitors as inhibitors of osteoclastic acid secretion and bone resorption.

29 September 2017

1 reference

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Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism

29 September 2017

1 reference

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A gene network regulating lysosomal biogenesis and function

29 September 2017

1 reference

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Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure

29 September 2017

1 reference

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Vesicular trafficking in osteoclasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase

29 September 2017

1 reference

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PPAR-gamma regulates osteoclastogenesis in mice

29 September 2017

1 reference

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Protein kinase C-beta inhibitor enzastaurin (LY317615.HCI) enhances radiation control of murine breast cancer in an orthotopic model of bone metastasis

29 September 2017

1 reference

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Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts

29 September 2017

1 reference

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Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

29 September 2017

1 reference

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The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Melanocytes and the microphthalmia transcription factor network

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Large-scale characterization of HeLa cell nuclear phosphoproteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Genetic regulation of osteoclast development and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice

29 September 2017

1 reference

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Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Bone resorption by osteoclasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

The osteoblast: a sophisticated fibroblast under central surveillance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Impaired gastric acidification negatively affects calcium homeostasis and bone mass.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Atp6v1c1 is an essential component of the osteoclast proton pump and in F-actin ring formation in osteoclasts

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Differential effects of calmodulin and protein kinase C antagonists on bone resorption and acid transport activity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650231

Participation of protein kinase C beta in osteoclast differentiation and function

4 December 2018

1 reference

12 December 2020

Bone embedding in pure methyl methacrylate at low temperature preserves enzyme activities

1 reference

12 December 2020

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1 reference

12 December 2020

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

1 reference

12 December 2020

v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.213827.113

1 reference

16 August 2017

1 reference

16 August 2017

1 reference