(Q36842724)

16 August 2017

1 reference

title

Effects of anticoagulant strategies on activation of inflammation and coagulation (English)

1 reference

16 August 2017

1 reference

1 reference

Clemens Feistritzer

1

1 reference

PubMed ID

17555371

16 August 2017

Christian J Wiedermann

series ordinal

2

1 reference

PubMed ID

17555371

16 August 2017

language of work or name

English

0 references

publication date

1 June 2007

1 reference

Expert Opinion on Biological Therapy

16 August 2017

1 reference

16 August 2017

7

1 reference

16 August 2017

6

1 reference

16 August 2017

855-870

1 reference

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

16 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Sepsis in 2003: are we still in the middle of nowhere?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Pro/con clinical debate: isolation precautions for all intensive care unit patients with methicillin-resistant Staphylococcus aureus colonization are essential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

The epidemiology of severe sepsis in England, Wales and Northern Ireland, 1996 to 2004: secondary analysis of a high quality clinical database, the ICNARC Case Mix Programme Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Early procoagulant shift in the bronchoalveolar compartment of patients with secondary peritonitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Four-day antithrombin therapy does not seem to attenuate hypercoagulability in patients suffering from sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Efficacy and safety of recombinant human activated protein C for severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Inflammation and the activated protein C anticoagulant pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protein C levels as a prognostic indicator of outcome in sepsis and related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Metalloproteolytic release of endothelial cell protein C receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol est

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protein C anticoagulant activity in relation to anti-inflammatory and anti-apoptotic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Blood coagulation-dependent inflammation. Coagulation-dependent inflammation and inflammation-dependent thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Extended evaluation of recombinant human activated protein C United States Trial (ENHANCE US): a single-arm, phase 3B, multicenter study of drotrecogin alfa (activated) in severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activation of protein C pathway in the airways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Expression and function of the endothelial protein C receptor in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Endothelial protein C receptor-dependent inhibition of human eosinophil chemotaxis by protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protein C and thrombomodulin in human acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C inhibits the expression of platelet-derived growth factor in the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Microhemodynamic and cellular mechanisms of activated protein C action during endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Inhibition of coagulation and inflammation by activated protein C or antithrombin reduces intestinal ischemia/reperfusion injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C reduces stress-induced gastric mucosal injury in rats by inhibiting the endothelial cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Prospective study of markers of hemostatic function with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Functional recovery after embolic stroke in rodents by activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protease-activated receptors-1 and -2 can mediate endothelial barrier protection: role in factor Xa signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Effect of drotrecogin alfa (activated) on human endothelial cell permeability and Rho kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Is APC activation of endothelial cell PAR1 important in severe sepsis?: No.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Recombinant human activated protein C attenuates the inflammatory response in endothelium and monocytes by modulating nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Gene expression profiling of inflamed human endothelial cells and influence of activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C induction of MCP-1 in human endothelial cells: a possible role for endothelial cell nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Mechanisms of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Apoptotic pathways: ten minutes to dead

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Modulation of monocyte function by activated protein C, a natural anticoagulant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C suppresses tissue factor expression on U937 cells in the endothelial protein C receptor-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Leukocyte and endothelial cell interactions in sepsis: relevance of the protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Characterization of protein C receptor expression in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C inhibits the release of macrophage inflammatory protein-1-alpha from THP-1 cells and from human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Effects of drotrecogin alfa (activated) in human endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Mechanisms by which soluble endothelial cell protein C receptor modulates protein C and activated protein C function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Identification of functional endothelial protein C receptor in human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Coagulation and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Thrombosis in inherited deficiencies of antithrombin, protein C, and protein S.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Serpin receptor 1: a hepatic receptor that mediates the clearance of antithrombin III-proteinase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Current drug treatment strategies for disseminated intravascular coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Clinical use of antithrombin III concentrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Determinants of specificity of factor xa interaction with its physiological inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Heparin-activated antithrombin interacts with the autolysis loop of target coagulation proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

How the protease thrombin talks to cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antithrombin III stimulates prostacyclin production by cultured aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antithrombin reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation through promotion of prostacyclin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antithrombin reduces compression-induced spinal cord injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antithrombin III attenuates pulmonary tissue injury caused by mesenteric ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antithrombin III prevents deleterious effects of remote ischemia-reperfusion injury on healing of colonic anastomoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Cell-surface heparan sulfate proteoglycan-mediated regulation of human neutrophil migration by the serpin antithrombin III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Syndecan-4 as antithrombin receptor of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Syndecan-4-dependent migration of human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Syndecan-4 as a molecule involved in defense mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

The serine protease inhibitor antithrombin III inhibits LPS-mediated NF-kappaB activation by TLR-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

NF-kappaB and the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Attenuation of leukocyte beta 2-integrin expression by antithrombin-III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Purification of a modified form of bovine antithrombin III as an HIV-1 CD8+ T-cell antiviral factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antiangiogenic activity of the cleaved conformation of the serpin antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

A novel anti-angiogenic form of antithrombin with retained proteinase binding ability and heparin affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

The heparin-binding site of antithrombin is crucial for antiangiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Substitution of antithrombin III in shock and DIC: a randomized study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

A systematic review of antithrombin concentrate use in patients with disseminated intravascular coagulation of severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C variants with normal cytoprotective but reduced anticoagulant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.6.855

Activated protein C reduces the severity of compression-induced spinal cord injury in rats by inhibiting activation of leukocytes

21 January 2018

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1523/JNEUROSCI.18-04-01393.1998

Identifiers

DOI

10.1517/14712598.7.6.855

1 reference

16 August 2017

1 reference

PubMed ID

17555371