(Q36851953)

16 August 2017

Crystal structure of the complex between thrombin and the central "E" region of fibrin (English)

1 reference

16 August 2017

Igor Pechik

1

1 reference

16 August 2017

Joel Madrazo

2

1 reference

16 August 2017

Michael W Mosesson

3

1 reference

16 August 2017

Irene Hernandez

4

1 reference

16 August 2017

Gary L Gilliland

5

1 reference

16 August 2017

Leonid Medved

6

1 reference

16 August 2017

language of work or name

English

0 references

publication date

20 February 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

101

1 reference

16 August 2017

9

1 reference

16 August 2017

2718-2723

1 reference

SHELXL: high-resolution refinement

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of native chicken fibrinogen at 2.7 A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of the central region of bovine fibrinogen (E5 fragment) at 1.4-A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The structure and function of the alpha C domains of fibrinogen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The finer things in X-ray diffraction data collection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Detecting and overcoming crystal twinning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen and fibrin--proteins with complex roles in hemostasis and thrombosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Strategy for recombinant multichain protein synthesis: fibrinogen B beta-chain variants as thrombin substrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The fibrinogen sequences that interact with thrombin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Thrombin interactions with fibrinogen and fibrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

A model for the specificity of fibrinogen cleavage by thrombin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Spatial structure of thrombin as a guide to its multiple sites of interaction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen degradation by hementin, a fibrinogenolytic anticoagulant from the salivary glands of the leech Haementeria ghilianii

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

29 September 2017

Fibrinogen and fibrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

High-resolution NMR studies of fibrinogen-like peptides in solution: interaction of thrombin with residues 1-23 of the A alpha chain of human fibrinogen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The structure of a complex of recombinant hirudin and human alpha-thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Molecular basis of fibrinogen Naples associated with defective thrombin binding and thrombophilia. Homozygous substitution of B beta 68 Ala----Thr

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The interaction of thrombin with fibrinogen. A structural basis for its specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen ""New York"--an abnormal fibrinogen associated with thromboembolism: functional evaluation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Functional mapping of the surface residues of human thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Inhibited thrombins. Interactions with fibrinogen and fibrin

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Fibrinogen assembly and crosslinking on a fibrin fragment E template.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365687

Analysis of fibrinogen alpha residues 27-50: interactions with thrombin

4 September 2018

1 reference

12 December 2020

Identification and characterization of the thrombin binding sites on fibrin

1 reference

12 December 2020

Characterization of fibrinogen New York 1. A dysfunctional fibrinogen with a deletion of B beta(9-72) corresponding exactly to exon 2 of the gene

1 reference

12 December 2020

Thrombin activity of fibrin thrombi and soluble plasmic derivatives

1 reference

12 December 2020

A role for platelets and thrombin in the juvenile stroke of two siblings with defective thrombin-adsorbing capacity of fibrin(ogen)

1 reference

12 December 2020

Studies on the mechanism of thrombin. Interaction with fibrin

1 reference

12 December 2020

The polymerization and thrombin-binding properties of des-(B beta 1-42)-fibrin

1 reference

12 December 2020

Fibrinogen Milano II: a congenital dysfibrinogenaemia associated with juvenile arterial and venous thrombosis

1 reference

12 December 2020

Formation of a ternary complex between thrombin, fibrin monomer, and heparin influences the action of thrombin on its substrates

1 reference

12 December 2020

Anion-binding exosite of human alpha-thrombin and fibrin(ogen) recognition

1 reference

12 December 2020

Antithrombin I. Inhibition of thrombin generation in plasma by fibrin formation

1 reference

12 December 2020

Three-dimensional modeling of thrombin-fibrinogen interaction

1 reference

12 December 2020

Thrombin, fibrin and platelets: a resonance loop in which von Willebrand factor is a necessary link

1 reference

12 December 2020

Inactivation of thrombin by antithrombin is accompanied by inactivation of regulatory exosite I

1 reference

12 December 2020

Identification of critical residues on thrombin mediating its interaction with fibrin

1 reference

12 December 2020

Binding of fibrin monomer and heparin to thrombin in a ternary complex alters the environment of the thrombin catalytic site, reduces affinity for hirudin, and inhibits cleavage of fibrinogen

1 reference

12 December 2020

The binding of thrombin by fibrin

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0303440101

1 reference

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

14978285

1 reference