(Q36853224)

English

Conserved Asp327 of walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis

scientific article published on December 2006

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scholarly article

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Europe PubMed Central

PMC publication ID

16 August 2017

Conserved Asp327 of walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis (English)

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Europe PubMed Central

PMC publication ID

16 August 2017

Candida albicans

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inferred from title

Rajendra Prasad

7

object named as

Rajendra Prasad

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Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Versha Rai

1

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Europe PubMed Central

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16 August 2017

Manisha Gaur

2

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Europe PubMed Central

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16 August 2017

Sudhanshu Shukla

3

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Europe PubMed Central

PMC publication ID

16 August 2017

Suneet Shukla

4

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Europe PubMed Central

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16 August 2017

Suresh V Ambudkar

5

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Europe PubMed Central

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16 August 2017

Sneha Sudha Komath

6

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16 August 2017

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publication date

1 December 2006

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Europe PubMed Central

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16 August 2017

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Europe PubMed Central

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16 August 2017

45

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Europe PubMed Central

PMC publication ID

16 August 2017

49

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

14726-14739

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Nucleotide binding domain interactions during the mechanochemical reaction cycle of ATP-binding cassette transporters

1 reference

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Nucleotide dissociation from NBD1 promotes solute transport by MRP1.

1 reference

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29 September 2017

Functional characterization of Candida albicans ABC transporter Cdr1p.

1 reference

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29 September 2017

Structure and function of efflux pumps that confer resistance to drugs

1 reference

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29 September 2017

Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis

1 reference

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Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures.

1 reference

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ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

1 reference

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29 September 2017

Drug resistance in yeasts--an emerging scenario

1 reference

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29 September 2017

Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters

1 reference

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29 September 2017

Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters

1 reference

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29 September 2017

A common mechanism for ATP hydrolysis in ABC transporter and helicase superfamilies

1 reference

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29 September 2017

The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter

1 reference

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29 September 2017

Distinct functions of the ATP binding cassettes of transporters associated with antigen processing: a mutational analysis of Walker A and B sequences

1 reference

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29 September 2017

Mutational analysis of conserved carboxylate residues in the nucleotide binding sites of P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526123

29 September 2017

Colorimetric protein assay techniques.

1 reference

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29 September 2017

Crystal structure of the ATP-binding subunit of an ABC transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526123

29 September 2017

ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains

1 reference

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29 September 2017

Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

1 reference

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29 September 2017

Major facilitator superfamily

1 reference

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29 September 2017

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

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29 September 2017

Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

1 reference

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29 September 2017

Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.

1 reference

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29 September 2017

Complete inventory of the yeast ABC proteins

1 reference

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29 September 2017

VMD: visual molecular dynamics

1 reference

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29 September 2017

Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526123

29 September 2017

Comparative protein modelling by satisfaction of spatial restraints

1 reference

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29 September 2017

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526123

29 September 2017

Stereochemical quality of protein structure coordinates

1 reference

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29 September 2017

Both ATP sites of human P-glycoprotein are essential but not symmetric

1 reference

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27 June 2018

One intact ATP-binding subunit is sufficient to support ATP hydrolysis and translocation in an ABC transporter, the histidine permease

1 reference

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27 June 2018

Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526123

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Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance.

1 reference

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4 September 2018

ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry

1 reference

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Proteomic response to amino acid starvation in Candida albicans and Saccharomyces cerevisiae

1 reference

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Analysis of catalytic carboxylate mutants E552Q and E1197Q suggests asymmetric ATP hydrolysis by the two nucleotide-binding domains of P-glycoprotein

1 reference

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Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump

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The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA.

1 reference

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Importance of the conserved Walker B glutamate residues, 556 and 1201, for the completion of the catalytic cycle of ATP hydrolysis by human P-glycoprotein (ABCB1).

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/17144665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the non-drug transporter C

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of polymorphic mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance, and its in vitro transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI061535T

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

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