(Q36854289)

16 August 2017

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title

Chromatin dynamics and the preservation of genetic information (English)

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16 August 2017

Jessica A Downs

1

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Michel C. Nussenzweig

series ordinal

2

object named as

Michel C Nussenzweig

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16 August 2017

André Nussenzweig

3

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PubMed ID

17581578

16 August 2017

language of work or name

English

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publication date

1 June 2007

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16 August 2017

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16 August 2017

447

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16 August 2017

7147

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16 August 2017

951-958

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https://scigraph.springernature.com/pub.10.1038/nature05980

16 August 2017

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cites work

Focusing on foci: H2AX and the recruitment of DNA-damage response factors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

H2B (Ser10) phosphorylation is induced during apoptosis and meiosis in S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

SWI-SNF complex participation in transcriptional activation at a step subsequent to activator binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone H4-K16 acetylation controls chromatin structure and protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Changes in nuclease sensitivity of mammalian cells after irradiation with 60Co gamma-rays

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Interfaces between the detection, signaling, and repair of DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

The DNA-dependent protein kinase: the director at the end.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

TopBP1 activates the ATR-ATRIP complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Spatio-temporal dynamics of chromatin containing DNA breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Identification of multiple distinct Snf2 subfamilies with conserved structural motifs.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Genes required for ionizing radiation resistance in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Human SWI/SNF nucleosome remodeling activity is partially inhibited by linker histone H1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A chromatin remodelling complex involved in transcription and DNA processing.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Control of sister chromatid recombination by histone H2AX.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Phosphorylation of histone H2B at DNA double-strand breaks.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone modifications associated with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Recruitment of the type B histone acetyltransferase Hat1p to chromatin is linked to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Involvement of human MOF in ATM function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Tails of histones lost

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

AID to overcome the limitations of genomic information

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Human lymphoblastoid proteome analysis reveals a role for the inhibitor of acetyltransferases complex in DNA double-strand break response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Chromatin disruption and modification

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Crystal structure of the nucleosome core particle at 2.8 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05980

7 January 2021

Identifiers

DOI

10.1038/NATURE05980

1 reference

16 August 2017

1 reference

PubMed ID

17581578