(Q36857449)

16 August 2017

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title

Modeling metastatic breast cancer in mice (English)

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16 August 2017

metastatic breast cancer

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Jos Jonkers

1

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PubMed ID

17587153

16 August 2017

Patrick W B Derksen

series ordinal

2

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16 August 2017

1 September 2007

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Journal of Mammary Gland Biology and Neoplasia

16 August 2017

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16 August 2017

12

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16 August 2017

191-203

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16 August 2017

2-3

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https://scigraph.springernature.com/pub.10.1007/s10911-007-9050-8

16 August 2017

0 references

cites work

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Breast cancer: relationship between the size of the primary tumour and the probability of metastatic dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Stromal fibroblasts in cancer: a novel tumor-promoting cell type

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Position-independent expression of the ovine beta-lactoglobulin gene in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-007-9050-8

High-resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histologic and genetic subgroups of invasive breast cancer.

21 January 2018

1 reference

12 December 2020

Interleukin 6: insights to its function in skin by overexpression in transgenic mice

1 reference

12 December 2020

Establishing a framework for the functional mammary gland: from endocrinology to morphology

1 reference

12 December 2020

Pathological prognostic factors in breast cancer. III. Vascular invasion: relationship with recurrence and survival in a large study with long-term follow-up

1 reference

12 December 2020

Radiation resistance and stem-like cells in brain tumors.

1 reference

12 December 2020

From genetic abnormality to metastases: murine models of breast cancer and their use in the development of anticancer therapies

1 reference

12 December 2020

Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.

1 reference

12 December 2020

Conditional control of gene expression in the mouse

1 reference

12 December 2020

Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis

1 reference

12 December 2020

Breast tumor cell lines from pleural effusions

1 reference

12 December 2020

Shedding light onto live molecular targets

1 reference

12 December 2020

Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis

1 reference

12 December 2020

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

1 reference

12 December 2020

Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice

1 reference

12 December 2020

Animal models of bone metastasis

1 reference

12 December 2020

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

1 reference

12 December 2020

Tumor metastasis: mechanistic insights and clinical challenges

1 reference

12 December 2020

Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models

1 reference

12 December 2020

Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours

1 reference

12 December 2020

Stromal effects on mammary gland development and breast cancer

1 reference

12 December 2020

Modeling metastasis in vivo

1 reference

12 December 2020

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

1 reference

12 December 2020

Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice

1 reference

12 December 2020

CD44 attenuates metastatic invasion during breast cancer progression

1 reference

12 December 2020

Advancing animal models of neoplasia through in vivo bioluminescence imaging

1 reference

12 December 2020

Paradoxical roles of the immune system during cancer development

1 reference

12 December 2020

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

1 reference

12 December 2020

Molecular portraits of human breast tumours

1 reference

12 December 2020

Steroid receptors and their role in the biology and control of breast cancer growth

1 reference

12 December 2020

Side effects of adjuvant treatment of breast cancer

1 reference

12 December 2020

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

12 December 2020

Gene expression profiling predicts clinical outcome of breast cancer

1 reference

12 December 2020

Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice

1 reference

12 December 2020

Developmental and tissue-specific regulation of mouse telomerase and telomere length

1 reference

12 December 2020

The mutationally activated Met receptor mediates motility and metastasis

1 reference

12 December 2020

Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer.

1 reference

12 December 2020

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

1 reference

12 December 2020

Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1

1 reference

12 December 2020

Reconstruction of functionally normal and malignant human breast tissues in mice

1 reference

12 December 2020

Intravital imaging of cell movement in tumours

1 reference

12 December 2020

The Hallmarks of Cancer

1 reference

12 December 2020

A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology

1 reference

12 December 2020

Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

1 reference

12 December 2020

VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms

1 reference

12 December 2020

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

1 reference

12 December 2020

Development of a flexible and specific gene delivery system for production of murine tumor models

1 reference

12 December 2020

A multigenic program mediating breast cancer metastasis to bone

1 reference

12 December 2020

In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain.

1 reference

12 December 2020

On mammary stem cells

1 reference

12 December 2020

Gone but not forgotten

1 reference

12 December 2020

Familial cancer syndromes

1 reference

12 December 2020

Cell transformation by the middle T-antigen of polyoma virus

1 reference

12 December 2020

Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors

1 reference

12 December 2020

Global trends in breast cancer incidence and mortality 1973-1997.

1 reference

12 December 2020

Natural history of node-negative breast cancer: a study of 826 patients with long-term follow-up.

1 reference

12 December 2020

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

12 December 2020

Pathological prognostic factors in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma: a study of 644 patients with median follow-up of 18 years

1 reference

12 December 2020

Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

1 reference

12 December 2020

Prognosis and breast cancer. Recognition of lethal and favorable prognostic types

1 reference

12 December 2020

The consensus coding sequences of human breast and colorectal cancers

1 reference

12 December 2020

CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation

1 reference

12 December 2020

A novel orthotopic model of breast cancer metastasis to bone.

1 reference

12 December 2020

MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer

1 reference

12 December 2020

A mouse model of human breast cancer metastasis to human bone

1 reference

12 December 2020

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

12 December 2020

TP53 and breast cancer

1 reference

12 December 2020

Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography

1 reference

12 December 2020

Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription

1 reference

12 December 2020

Transcriptional activation by tetracyclines in mammalian cells

1 reference

12 December 2020

Probing the microenvironment of mammary tumors using multiphoton microscopy

1 reference

12 December 2020

Involvement of chemokine receptors in breast cancer metastasis

1 reference

12 December 2020

Invasive growth: a MET-driven genetic programme for cancer and stem cells

1 reference

12 December 2020

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

1 reference

12 December 2020

Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases

1 reference

12 December 2020

Breast carcinoma: Pattern of metastasis at autopsy

1 reference

12 December 2020

Species- and cell type-specific requirements for cellular transformation

1 reference

12 December 2020

Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways.

1 reference

12 December 2020

Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor

1 reference

12 December 2020

Effect of screening and adjuvant therapy on mortality from breast cancer

1 reference

12 December 2020

The epigenetic progenitor origin of human cancer

1 reference

12 December 2020

Trends in the usage of adjuvant systemic therapy for breast cancer in the Netherlands and its effect on mortality

1 reference

12 December 2020

Treatment of breast cancer

1 reference

12 December 2020

Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis

1 reference

12 December 2020

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis

1 reference

12 December 2020

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

1 reference

12 December 2020

Histopathology of salivary and mammary gland tumors in transgenic mice expressing a human Ha-ras oncogene

1 reference

12 December 2020

The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting

1 reference

12 December 2020

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

1 reference

12 December 2020

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1 reference

12 December 2020

A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland

1 reference

12 December 2020

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

12 December 2020

Overexpression of the RON gene in human breast carcinoma

1 reference

12 December 2020

Metastasizing mammary carcinomas in H19 enhancers-Igf2 transgenic mice

1 reference

12 December 2020

Breast cancer metastasis: markers and models

1 reference

12 December 2020

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene

1 reference

12 December 2020

Transplantation of a Human Mammary Carcinoma Cell Line (BT 20) Into Nude Mice2

1 reference

12 December 2020

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

12 December 2020

Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

1 reference

12 December 2020

Scaling down imaging: molecular mapping of cancer in mice

1 reference

12 December 2020

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1 reference

12 December 2020

Genes that mediate breast cancer metastasis to lung

1 reference

12 December 2020

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

1 reference

12 December 2020

Prospective identification of tumorigenic breast cancer cells

1 reference

12 December 2020

Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis

1 reference

12 December 2020

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

1 reference

12 December 2020

Mammary tumors induced by polyomavirus

1 reference

12 December 2020

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

1 reference

12 December 2020

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

1 reference

12 December 2020

Lapatinib plus capecitabine for HER2-positive advanced breast cancer

1 reference

12 December 2020

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

12 December 2020

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

12 December 2020

Reduced metastasis of transgenic mammary cancer in urokinase-deficient mice

1 reference

12 December 2020

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

1 reference

12 December 2020

The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy.

1 reference

12 December 2020

Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage

1 reference

12 December 2020

Conditional mouse models of sporadic cancer

1 reference

12 December 2020

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

1 reference

12 December 2020

Cancer. Addiction to oncogenes--the Achilles heal of cancer

1 reference

12 December 2020

Cancer genes and the pathways they control

1 reference

12 December 2020

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

12 December 2020

1 reference

12 December 2020

Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424).

1 reference

12 December 2020

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

1 reference

12 December 2020

Brief Communication: Growth of Human Normal and Neoplastic Mammary Tissues in the Cleared Mammary Fat Pad of the Nude Mouse2

1 reference

12 December 2020

Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant

1 reference

12 December 2020

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

1 reference

12 December 2020

10.1007/S10911-007-9050-8

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17587153