(Q36871985)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

1 reference

title

Targeting cancer stem cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

main subject

neoplastic stem cells

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Brynn T Kvinlaug

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

1 July 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

915-927

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Cytogenetically aberrant cells are present in the CD34+CD33-38-19- marrow compartment in children with acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Characterization of clonogenic multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Radial glia cells are candidate stem cells of ependymoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

21 January 2018

Brain tumour stem cells

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Neurocytoma is a tumor of adult neuronal progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Isolation and functional characterization of murine prostate stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

CD133, a novel marker for human prostatic epithelial stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Prostate cancer stem/progenitor cells: identification, characterization, and implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Stem cells for lung cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Identification of bronchioalveolar stem cells in normal lung and lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Identification of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Role of efflux pumps and metabolising enzymes in drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Mechanisms and strategies to overcome multiple drug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

HOX and non-HOX homeobox genes in leukemic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Deregulated homeobox gene expression in cancer: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The Hedgehog and Wnt signalling pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Stem cells and cancer; the polycomb connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

A role for Wnt signalling in self-renewal of haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Survival of acute myeloid leukemia cells requires PI3 kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Antileukemic activity of rapamycin in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

mTOR regulates cell survival after etoposide treatment in primary AML cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Recent advances in targeted therapy for non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Bleeding in carriers of hemophilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Preferential induction of apoptosis for primary human leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

The control of neural stem cells by morphogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

A perivascular niche for brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

An update on the role of epidermal growth factor receptor inhibitors in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Epidermal growth factor receptor/angiogenesis dual targeting: preclinical experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.915

10.1517/14728222.11.7.915

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17614760%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference