(Q36878827)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

0 references

1 reference

10

1 reference

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10 March 2020

author name string

Pinelopi P Kapitsinou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Ganeshkumar Rajendran

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Lindsay Astleford

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Mark Michael

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Michael P Schonfeld

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Timothy Fields

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Sheila Shay

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Jaketa L French

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

James West

9

1 reference

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10 March 2020

language of work or name

English

0 references

publication date

2 May 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

10 March 2020

published in

1 reference

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10 March 2020

volume

36

1 reference

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10 March 2020

issue

10

1 reference

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10 March 2020

page(s)

1584-1594

1 reference

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describes a project that uses

10 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4859687/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Genetic differences and aberrant methylation in the apelin system predict the risk of high-altitude pulmonary edema

29 September 2017

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29 September 2017

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Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation

29 September 2017

1 reference

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Allosteric inhibition of hypoxia inducible factor-2 with small molecules

29 September 2017

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Molecular pathogenesis of pulmonary arterial hypertension

29 September 2017

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A potential role for insulin resistance in experimental pulmonary hypertension

29 September 2017

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Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success

29 September 2017

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29 September 2017

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Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation

29 September 2017

1 reference

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Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Hypoxia-inducible factors and the response to hypoxic stress

29 September 2017

1 reference

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The HIF pathway and erythrocytosis

29 September 2017

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Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.

29 September 2017

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The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.

29 September 2017

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Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells

29 September 2017

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Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis

29 September 2017

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Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

29 September 2017

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29 September 2017

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Expanding chemical biology of 2-oxoglutarate oxygenases

29 September 2017

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Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

29 September 2017

1 reference

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HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes

29 September 2017

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Acute postnatal ablation of Hif-2alpha results in anemia

29 September 2017

1 reference

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Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

29 September 2017

1 reference

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Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology

29 September 2017

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Integration of oxygen signaling at the consensus HRE.

29 September 2017

1 reference

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The endothelin system in pulmonary arterial hypertension

29 September 2017

1 reference

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Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

29 September 2017

1 reference

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Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

29 September 2017

1 reference

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Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: role of hypoxia responsive element

29 September 2017

1 reference

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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

29 September 2017

1 reference

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The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

29 September 2017

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Targeted gene delivery of BMPR2 attenuates pulmonary hypertension.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859687

Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension

4 September 2018

1 reference

12 December 2020

Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis

1 reference

12 December 2020

Hypoxia and proinflammatory factors upregulate apelin receptor expression in human stellate cells and hepatocytes

1 reference

12 December 2020

von Hippel-Lindau disease

1 reference

12 December 2020

Hypoxia inducible factor regulates the cardiac expression and secretion of apelin

1 reference

12 December 2020

Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.01055-15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26976644%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference