(Q36885663)

16 August 2017

title

Pharmacology, pharmacokinetics and pharmacogenomics of paclitaxel (English)

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16 August 2017

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Helen Steed

1

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16 August 2017

Michael B Sawyer

series ordinal

2

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16 August 2017

publication date

1 July 2007

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16 August 2017

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16 August 2017

volume

8

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16 August 2017

issue

7

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16 August 2017

page(s)

803-815

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Paclitaxel and recombinant human granulocyte colony-stimulating factor as initial chemotherapy for metastatic breast cancer

16 August 2017

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Population pharmacokinetic modelling of unbound and total plasma concentrations of paclitaxel in cancer patients

21 January 2018

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21 January 2018

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Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy

21 January 2018

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Cytochromes P450 are expressed in proliferating cells in Barrett's metaplasia

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The effect of ketoconazole on the jejunal permeability and CYP3A metabolism of (R/S)-verapamil in humans

21 January 2018

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Isolation, structural determination, and biological activity of 6 alpha-hydroxytaxol, the principal human metabolite of taxol

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Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

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Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals

21 January 2018

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Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

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Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

21 January 2018

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Genetic contribution to variable human CYP3A-mediated metabolism

21 January 2018

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CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity

21 January 2018

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Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

21 January 2018

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

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Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver

21 January 2018

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21 January 2018

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Expression of a multidrug-resistance gene in human tumors and tissues

21 January 2018

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Gene amplification and expression in lung cancer cells with acquired paclitaxel resistance

21 January 2018

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Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples

21 January 2018

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Anticancer drugs induce mdr1 gene expression in recurrent ovarian cancer

21 January 2018

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Multidrug resistance gene-1 is a useful predictor of Paclitaxel-based chemotherapy for patients with ovarian cancer

21 January 2018

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P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance

21 January 2018

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21 January 2018

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

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mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy

21 January 2018

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Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropenia

21 January 2018

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Chronic idiopathic jaundice with unidentified pigment in liver cells; a new clinicopathologic entity with a report of 12 cases

21 January 2018

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Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

21 January 2018

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Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein

21 January 2018

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Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins

21 January 2018

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Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10)

21 January 2018

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Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel

21 January 2018

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Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics.

21 January 2018

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Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8).

21 January 2018

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Do beta-tubulin mutations have a role in resistance to chemotherapy?

21 January 2018

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Structure of the alpha beta tubulin dimer by electron crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.7.803

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.7.803

Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.7.803

Characterization of single-nucleotide polymorphisms in coding regions of human genes

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.8.7.803

Effect of several compounds on biliary excretion of paclitaxel and its metabolites in guinea-pigs

21 January 2018

1 reference

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Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively

21 January 2018

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The xenobiotic inhibitor profile of cytochrome P4502C8.

21 January 2018

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The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.7.803

21 January 2018

Identifiers

DOI

10.2217/14622416.8.7.803

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16 August 2017

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