(Q36887534)

16 August 2017

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title

Angiogenesis in brain tumours (English)

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16 August 2017

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1

Rakesh K Jain

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16 August 2017

2

Emmanuelle di Tomaso

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16 August 2017

6

Tracy T Batchelor

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16 August 2017

Dan G Duda

3

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16 August 2017

Jay S Loeffler

series ordinal

4

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16 August 2017

A Gregory Sorensen

series ordinal

5

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16 August 2017

language of work or name

English

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publication date

1 August 2007

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Nature Reviews Neuroscience

16 August 2017

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16 August 2017

8

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16 August 2017

610-622

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16 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrn2175

16 August 2017

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cites work

Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials

1 reference

Changing paradigms--an update on the multidisciplinary management of malignant glioma

31 March 2020

1 reference

Brain teasing effect of dexamethasone.

31 March 2020

1 reference

Transplacental carcinogenesis by stilbestrol

31 March 2020

1 reference

Angiogenesis: an organizing principle for drug discovery?

31 March 2020

1 reference

Lessons from phase III clinical trials on anti-VEGF therapy for cancer

31 March 2020

1 reference

Progress report on the potential of angiogenesis inhibitors for neuro-oncology

31 March 2020

1 reference

MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy.

31 March 2020

1 reference

Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy

31 March 2020

1 reference

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

31 March 2020

1 reference

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

31 March 2020

1 reference

Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma.

31 March 2020

1 reference

The seed and soil hypothesis: vascularisation and brain metastases

31 March 2020

1 reference

Mechanisms of disease: the blood-brain barrier

31 March 2020

1 reference

The biology of metastasis to a sanctuary site

31 March 2020

1 reference

Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

31 March 2020

1 reference

Tumour biology: herceptin acts as an anti-angiogenic cocktail.

31 March 2020

1 reference

Vessel tortuosity and brain tumor malignancy: a blinded study

31 March 2020

1 reference

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses

31 March 2020

1 reference

Vascular morphology and angiogenesis in glial tumors

31 March 2020

1 reference

Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors.

31 March 2020

1 reference

Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment

31 March 2020

1 reference

In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis.

31 March 2020

1 reference

The next frontier of molecular medicine: delivery of therapeutics.

31 March 2020

1 reference

Dissecting tumour pathophysiology using intravital microscopy

31 March 2020

1 reference

Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model

31 March 2020

1 reference

Grading of CNS neoplasms using continuous arterial spin labeled perfusion MR imaging at 3 Tesla.

31 March 2020

1 reference

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

31 March 2020

1 reference

Angiogenesis in cancer and other diseases

31 March 2020

1 reference

Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy

31 March 2020

1 reference

Vascular endothelial growth factor: basic science and clinical progress

31 March 2020

1 reference

The role of nitric oxide in tumour progression

31 March 2020

1 reference

Tumor induction of VEGF promoter activity in stromal cells

31 March 2020

1 reference

Interstitial fluid pressure in intracranial tumours in patients and in rodents

31 March 2020

1 reference

Barriers to drug delivery in solid tumors

31 March 2020

1 reference

"Artificial lymphatic system": a new approach to reduce interstitial hypertension and increase blood flow, pH and pO2 in solid tumors

31 March 2020

1 reference

During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium

31 March 2020

1 reference

Interaction of activated natural killer cells with normal and tumor vessels in cranial windows in mice

31 March 2020

1 reference

Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

31 March 2020

1 reference

Vessel co-option: how tumors obtain blood supply in the absence of sprouting angiogenesis.

31 March 2020

1 reference

Pathology: cancer cells compress intratumour vessels.

31 March 2020

1 reference

Angiogenesis in life, disease and medicine

31 March 2020

1 reference

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

31 March 2020

1 reference

Vascular-specific growth factors and blood vessel formation

31 March 2020

1 reference

Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors

31 March 2020

1 reference

Incorporation of bone marrow-derived Flk-1-expressing CD34+ cells in the endothelium of tumor vessels in the mouse brain.

31 March 2020

1 reference

Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes.

31 March 2020

1 reference

Vascular morphogenesis and remodeling in a human tumor xenograft: blood vessel formation and growth after ovariectomy and tumor implantation

31 March 2020

1 reference

Angiogenesis-independent tumor growth mediated by stem-like cancer cells

31 March 2020

1 reference

Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option

31 March 2020

1 reference

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

31 March 2020

1 reference

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

31 March 2020

1 reference

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

31 March 2020

1 reference

Angiogenesis in gliomas: biology and molecular pathophysiology

31 March 2020

1 reference

Prominent Microvascular Proliferation in Clinically Aggressive Neuroblastoma

31 March 2020

1 reference

The role of angiopoietins during angiogenesis in gliomas

31 March 2020

1 reference

Angiopoietin-1 promotes tumor angiogenesis in a rat glioma model

31 March 2020

1 reference

Role of integrins in cell invasion and migration

31 March 2020

1 reference

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

31 March 2020

1 reference

Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity

31 March 2020

1 reference

In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor.

31 March 2020

1 reference

Molecular regulation of vessel maturation

31 March 2020

1 reference

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain.

31 March 2020

1 reference

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis.

31 March 2020

1 reference

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

31 March 2020

1 reference

Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs

31 March 2020

1 reference

The PDGF family: four gene products form five dimeric isoforms

31 March 2020

1 reference

Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation

31 March 2020

1 reference

Platelet-derived growth factor B retention is essential for development of normal structure and function of conduit vessels and capillaries

31 March 2020

1 reference

Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.

31 March 2020

1 reference

Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma.

31 March 2020

1 reference

The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis

31 March 2020

1 reference

Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice

31 March 2020

1 reference

The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis

31 March 2020

1 reference

CXCR4 and SDF1 expression in human meningiomas: a proliferative role in tumoral meningothelial cells in vitro

31 March 2020

1 reference

Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration.

31 March 2020

1 reference

Chemokine stromal cell-derived factor 1alpha induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals

31 March 2020

1 reference

Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion

31 March 2020

1 reference

Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells

31 March 2020

1 reference

Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells.

31 March 2020

1 reference

VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells

31 March 2020

1 reference

Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

31 March 2020

1 reference

Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles.

31 March 2020

1 reference

31 March 2020

1 reference

Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function

31 March 2020

1 reference

Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis.

31 March 2020

1 reference

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

31 March 2020

1 reference

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

31 March 2020

1 reference

Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery

31 March 2020

1 reference

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

31 March 2020

1 reference

Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

31 March 2020

1 reference

Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

31 March 2020

1 reference

Cellular abnormalities of blood vessels as targets in cancer

31 March 2020

1 reference

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

31 March 2020

1 reference

Antiangiogenic therapy: a universal chemosensitization strategy for cancer?

31 March 2020

1 reference

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice

31 March 2020

1 reference

How does antiangiogenic therapy affect brain tumor response to radiation?

31 March 2020

1 reference

A perivascular niche for brain tumor stem cells

31 March 2020

1 reference

Effect of bevacizumab on radiation necrosis of the brain.

31 March 2020

1 reference

Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition

31 March 2020

1 reference

Angiogenesis in gliomas: imaging and experimental therapeutics

31 March 2020

1 reference

A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood

31 March 2020

1 reference

Glucocorticoid treatment for brain metastases and epidural spinal cord compression: a review

31 March 2020

1 reference

Comparison of diameter and perimeter methods for tumor volume calculation

31 March 2020

1 reference

Magnetic resonance as a cancer imaging biomarker

31 March 2020

1 reference

Imaging angiogenesis: applications and potential for drug development

31 March 2020

1 reference

31 March 2020

Tumor hypoxia imaging

1 reference

Assessment of brain tumor angiogenesis inhibitors using perfusion magnetic resonance imaging: quality and analysis results of a phase I trial.

31 March 2020

1 reference

Reproducibility of quantitative dynamic contrast-enhanced MRI in newly presenting glioma.

31 March 2020

1 reference

Tumor-specific positron emission tomography imaging in patients: [18F] fluorodeoxyglucose and beyond

31 March 2020

1 reference

Nuclear imaging probes: from bench to bedside

31 March 2020

1 reference

Common mechanisms of nerve and blood vessel wiring

31 March 2020

1 reference

A role for axon guidance receptors and ligands in blood vessel development and tumor angiogenesis

31 March 2020

1 reference

Netrins promote developmental and therapeutic angiogenesis.

31 March 2020

1 reference

Netrins: beyond the brain

31 March 2020

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Bidirectional Eph-ephrin signaling during axon guidance

31 March 2020

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Regulation of angiogenesis by Eph-ephrin interactions

31 March 2020

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

31 March 2020

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Soluble neuropilin targeted to the skin inhibits vascular permeability

31 March 2020

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Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype

31 March 2020

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Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

31 March 2020

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Pleiotropy of tissue-specific growth factors: from neurons to vessels via the bone marrow

31 March 2020

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Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials

31 March 2020

1 reference

Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma

31 March 2020

1 reference

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients

31 March 2020

1 reference

Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

31 March 2020

1 reference

Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis

31 March 2020

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VEGF-A induces angiogenesis, arteriogenesis, lymphangiogenesis, and vascular malformations

31 March 2020

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Correlation of relative permeability and relative cerebral blood volume in high-grade cerebral neoplasms.

31 March 2020

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Diffusion-weighted and perfusion MR imaging for brain tumor characterization and assessment of treatment response

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRN2175

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16 August 2017

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