(Q36898459)

English

CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves

scientific article published on 13 May 2016

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves (English)

1 reference

Europe PubMed Central

16 August 2017

amyotrophic lateral sclerosis

0 references

7

object named as

Xavier Navarro

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object named as

Renzo Mancuso

2

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Ruben Lopez-vales

object named as

Ruben López-Vales

9

0 references

Diego Gómez-Nicola

object named as

Diego Gomez-Nicola

8

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author name string

Anna Martínez-Muriana

1

1 reference

Europe PubMed Central

16 August 2017

Isaac Francos-Quijorna

3

1 reference

Europe PubMed Central

16 August 2017

Adrian Olmos-Alonso

4

1 reference

Europe PubMed Central

16 August 2017

Rosario Osta

5

1 reference

Europe PubMed Central

16 August 2017

V Hugh Perry

6

1 reference

Europe PubMed Central

16 August 2017

language of work or name

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publication date

13 May 2016

1 reference

Europe PubMed Central

16 August 2017

Scientific Reports

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Europe PubMed Central

16 August 2017

6

1 reference

Europe PubMed Central

16 August 2017

25663

1 reference

Europe PubMed Central

16 August 2017

copyright license

Creative Commons Attribution 4.0 International

13 May 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4865981/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1038/srep25663

0 references

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology

1 reference

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29 September 2017

Targeting the colony stimulating factor 1 receptor alleviates two forms of Charcot-Marie-Tooth disease in mice

1 reference

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Microglial dynamics and role in the healthy and diseased brain: a paradigm of functional plasticity

1 reference

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Sustained inhibition of receptor tyrosine kinases and macrophage depletion by PLX3397 and rapamycin as a potential new approach for the treatment of MPNSTs

1 reference

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Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis

1 reference

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Necroptosis drives motor neuron death in models of both sporadic and familial ALS.

1 reference

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A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model

1 reference

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29 September 2017

Inflammation and neurovascular changes in amyotrophic lateral sclerosis.

1 reference

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Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications.

1 reference

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Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.

1 reference

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Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D1

1 reference

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Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase

1 reference

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29 September 2017

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

1 reference

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29 September 2017

Multidimensional profiling of CSF1R screening hits and inhibitors: assessing cellular activity, target residence time, and selectivity in a higher throughput way.

1 reference

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29 September 2017

In Vivo imaging reveals distinct inflammatory activity of CNS microglia versus PNS macrophages in a mouse model for ALS

1 reference

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Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis.

1 reference

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Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice

1 reference

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T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?

1 reference

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T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.

1 reference

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Interactions between Schwann cells and macrophages in injury and inherited demyelinating disease

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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

1 reference

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4865981

29 September 2017

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4865981

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Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4865981

29 September 2017

Optimal methods to characterize the G93A mouse model of ALS.

1 reference

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29 September 2017

Unraveling the mechanisms involved in motor neuron degeneration in ALS

1 reference

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Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases

1 reference

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Colony-stimulating factor-1 receptor

1 reference

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Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

1 reference

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Regulation of microglial proliferation during chronic neurodegeneration

1 reference

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1 reference

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27 June 2018

Evidence for peripheral immune activation in amyotrophic lateral sclerosis.

1 reference

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1 reference

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1 reference

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4 September 2018

Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4865981

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1 reference

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Origin and distribution of bone marrow-derived cells in the central nervous system in a mouse model of amyotrophic lateral sclerosis.

1 reference

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Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

1 reference

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Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue

1 reference

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

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4 September 2018

Macrophage Response to Peripheral Nerve Injury: The Quantitative Contribution of Resident and Hematogenous Macrophages

2 references

https://api.crossref.org/works/10.1038%2FSREP25663

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/27174644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/27174644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27174644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/27174644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP25663

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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