(Q36900911)

17 August 2017

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title

The multiple roles of the Mre11 complex for meiotic recombination (English)

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Gene Ontology release 2020-05-02

17 August 2017

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Valérie Borde

1

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17 August 2017

1 January 2007

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17 August 2017

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17 August 2017

15

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17 August 2017

551-563

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17 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s10577-007-1147-9

17 August 2017

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cites work

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1007%2FS10577-007-1147-9

Budding Yeast Sae2 is an In Vivo Target of the Mec1 and Tel1 Checkpoint Kinases During Meiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10577-007-1147-9

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10577-007-1147-9

A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10577-007-1147-9

Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10577-007-1147-9

C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint

21 January 2018

1 reference

12 December 2020

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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12 December 2020

Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae

1 reference

12 December 2020

Meiotic cells monitor the status of the interhomolog recombination complex

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12 December 2020

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

1 reference

12 December 2020

XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination

1 reference

12 December 2020

Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formation

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12 December 2020

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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12 December 2020

Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

1 reference

12 December 2020

Meiotic chromosomes: integrating structure and function

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12 December 2020

Different roles of the Mre11 complex in the DNA damage response in Aspergillus nidulans

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12 December 2020

AtSPO11-1 is necessary for efficient meiotic recombination in plants

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12 December 2020

Meiotic recombination remote from prominent DNA break sites in S. pombe

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12 December 2020

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

1 reference

12 December 2020

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

12 December 2020

The Mre11 nuclease is not required for 5' to 3' resection at multiple HO-induced double-strand breaks

1 reference

12 December 2020

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

1 reference

12 December 2020

Identification and functional consequences of a novel MRE11 mutation affecting 10 Saudi Arabian patients with the ataxia telangiectasia-like disorder.

1 reference

12 December 2020

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

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12 December 2020

Mre11 deficiency in Arabidopsis is associated with chromosomal instability in somatic cells and Spo11-dependent genome fragmentation during meiosis

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12 December 2020

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

1 reference

12 December 2020

Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae.

1 reference

12 December 2020

Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae.

1 reference

12 December 2020

Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1

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12 December 2020

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

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12 December 2020

Brca1 controls homology-directed DNA repair

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12 December 2020

Severe developmental defects, hypersensitivity to DNA-damaging agents, and lengthened telomeres in Arabidopsis MRE11 mutants

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12 December 2020

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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12 December 2020

Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism

1 reference

12 December 2020

Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

1 reference

12 December 2020

Isolation and characterization of novel xrs2 mutations in Saccharomyces cerevisiae

1 reference

12 December 2020

Yeast Xrs2 Binds DNA and Helps Target Rad50 and Mre11 to DNA Ends

1 reference

12 December 2020

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

1 reference

12 December 2020

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

1 reference

12 December 2020

Replication-dependent early meiotic requirement for Spo11 and Rad50

1 reference

12 December 2020

Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae

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12 December 2020

Requirement of the MRN complex for ATM activation by DNA damage

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12 December 2020

Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants

1 reference

12 December 2020

Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

1 reference

12 December 2020

Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

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12 December 2020

Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

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12 December 2020

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12 December 2020

Chromosome dynamics in rad12 mutants of Coprinus cinereus

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12 December 2020

Disruption of the Arabidopsis RAD50 gene leads to plant sterility and MMS sensitivity

1 reference

12 December 2020

Xrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination

1 reference

12 December 2020

Association of Mre11p with double-strand break sites during yeast meiosis.

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12 December 2020

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

1 reference

12 December 2020

The Rad50 hook domain is a critical determinant of Mre11 complex functions

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12 December 2020

Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae.

1 reference

12 December 2020

Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes

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12 December 2020

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

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12 December 2020

A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2.

1 reference

12 December 2020

Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity.

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12 December 2020

Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism

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12 December 2020

A murine model of Nijmegen breakage syndrome

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12 December 2020

The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

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12 December 2020

Conserved and nonconserved proteins for meiotic DNA breakage and repair in yeasts

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12 December 2020

mre11S--a yeast mutation that blocks double-strand-break processing and permits nonhomologous synapsis in meiosis

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12 December 2020

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

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12 December 2020

The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis

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12 December 2020

Mechanism and control of meiotic recombination initiation

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12 December 2020

Complex formation and functional versatility of Mre11 of budding yeast in recombination

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12 December 2020

Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA

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12 December 2020

Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity

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12 December 2020

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

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12 December 2020

Meiotic defects in the Arabidopsis rad50 mutant point to conservation of the MRX complex function in early stages of meiotic recombination

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12 December 2020

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

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12 December 2020

NBS1 and its functional role in the DNA damage response

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12 December 2020

An mre11 mutant of Coprinus cinereus has defects in meiotic chromosome pairing, condensation and synapsis.

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12 December 2020

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity

1 reference

12 December 2020

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

1 reference

12 December 2020

The Aspergillus nidulans sldI(RAD50) gene interacts with bimE(APC1), a homologue of an anaphase-promoting complex subunit

1 reference

12 December 2020

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

12 December 2020

The yeast Xrs2 complex functions in S phase checkpoint regulation

1 reference

12 December 2020

Endonucleolytic processing of covalent protein-linked DNA double-strand breaks

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12 December 2020

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

1 reference

12 December 2020

Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

1 reference

12 December 2020

10.1007/S10577-007-1147-9

Identifiers

DOI

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release_xhh7komvbnfwhittngnzssntse

17 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/xhh7komvbnfwhittngnzssntse

24 November 2022

mapped directly with Wikidata item

PubMed ID

17674145

1 reference

PubMed ID

17674145