(Q36903106)

English

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.

scientific article published on 29 January 2013

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22 February 2020

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies (English)

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22 February 2020

Lucas A Smolders

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22 February 2020

Marian Groot Koerkamp

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Laura B Creemers

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22 February 2020

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Björn P Meij

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David Onis

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Frank M Riemers

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Niklas Bergknut

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Richard Wubbolts

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22 February 2020

Guy C M Grinwis

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Martin Houweling

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Dik van Leenen

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Frank C P Holstege

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22 February 2020

Herman A W Hazewinkel

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22 February 2020

Louis C Penning

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22 February 2020

Marianna A Tryfonidou

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22 February 2020

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29 January 2013

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22 February 2020

Arthritis Research and Therapy

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22 February 2020

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22 February 2020

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22 February 2020

R23

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22 February 2020

describes a project that uses

object named as

CellProfiler

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

https://scigraph.springernature.com/pub.10.1186/ar4157

0 references

Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue.

1 reference

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29 September 2017

Caveolin-1: role in cell signaling

1 reference

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29 September 2017

Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration

1 reference

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29 September 2017

Notochordal cells in the adult intervertebral disc: new perspective on an old question

1 reference

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29 September 2017

Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells.

1 reference

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29 September 2017

Impact of RNA degradation on gene expression profiling.

1 reference

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29 September 2017

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord

1 reference

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29 September 2017

Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers

1 reference

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29 September 2017

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

1 reference

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29 September 2017

Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord.

1 reference

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29 September 2017

The regenerative capacity of the notochordal cell: tissue constructs generated in vitro under hypoxic conditions

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29 September 2017

Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders

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29 September 2017

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Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis

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29 September 2017

Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.

1 reference

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29 September 2017

Disc regeneration: a glimpse of the future.

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Surgical interventions for lumbar disc prolapse: updated Cochrane Review

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29 September 2017

Caveolin-1 is required for lateral line neuromast and notochord development

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29 September 2017

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29 September 2017

Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin

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29 September 2017

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

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29 September 2017

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

1 reference

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29 September 2017

Wnt signalling in rheumatoid arthritis

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29 September 2017

Critical analysis of trends in fusion for degenerative disc disease over the past 20 years: influence of technique on fusion rate and clinical outcome

1 reference

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29 September 2017

The three‐dimensional architecture of the notochordal nucleus pulposus: novel observations on cell structures in the canine intervertebral disc

1 reference

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29 September 2017

Monitoring global messenger RNA changes in externally controlled microarray experiments.

1 reference

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29 September 2017

Multiple functions of caveolin-1.

1 reference

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29 September 2017

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

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29 September 2017

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

1 reference

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29 September 2017

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

1 reference

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29 September 2017

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

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29 September 2017

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

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29 September 2017

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

1 reference

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29 September 2017

A new mathematical model for relative quantification in real-time RT-PCR

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29 September 2017

Plakoglobin and beta-catenin: protein interactions, regulation and biological roles

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29 September 2017

Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3672710

29 September 2017

Adjacent-segment degeneration after lumbar fusion: a review of clinical, biomechanical, and radiologic studies

1 reference

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29 September 2017

A new secreted protein that binds to Wnt proteins and inhibits their activities

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29 September 2017

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29 September 2017

Wnt signaling: a common theme in animal development

1 reference

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29 September 2017

Caveolae: where incoming and outgoing messengers meet

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29 September 2017

Expression of cytokeratin and vimentin in nucleus pulposus cells

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29 September 2017

Demonstration of cytokeratins and an epithelial membrane antigen in chordomas and human fetal notochord

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29 September 2017

Morphological studies of the canine intervertebral disc. The assignment of the beagle to the achondroplastic classification

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29 September 2017

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27 June 2018

Adaptable gene-specific dye bias correction for two-channel DNA microarrays

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27 June 2018

Caveolin-1 knockout mice have increased bone size and stiffness

1 reference

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27 June 2018

Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes.

1 reference

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27 June 2018

The T genes in embryogenesis.

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27 June 2018

Accelerated degeneration of the segment adjacent to a lumbar fusion

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27 June 2018

Change of Disc Height, Radial Disc Bulge, and Intradiscal Pressure From Discectomy An in Vitro Investigation on Human Lumbar Discs

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27 June 2018

Intervertebral disc-derived stem cells: implications for regenerative medicine and neural repair.

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4 September 2018

Coagulation aggravates blood-induced joint damage in dogs

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4 September 2018

Elevation of cartilage AGEs does not accelerate initiation of canine experimental osteoarthritis upon mild surgical damage.

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4 September 2018

Kinematic motion patterns of the cranial and caudal canine cervical spine

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4 September 2018

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4 September 2018

The enigma that is the nucleus pulposus cell: the search goes on.

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4 September 2018

Low-field magnetic resonance imaging findings of the caudal portion of the cervical region in clinically normal Doberman Pinschers and Foxhounds.

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4 September 2018

Does loading influence the severity of cartilage degeneration in the canine Groove-model of OA?

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4 September 2018

The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation

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4 September 2018

Evidence for skeletal progenitor cells in the degenerate human intervertebral disc.

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4 September 2018

Notochord cells regulate intervertebral disc chondrocyte proteoglycan production and cell proliferation.

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4 September 2018

Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis.

1 reference

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4 September 2018

Endogenous Wnt signaling promotes proliferation and suppresses osteogenic differentiation in human adipose derived stromal cells

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4 September 2018

The subcellular localization control of integrin linked kinase 1 through its protein-protein interaction with caveolin-1.

1 reference

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4 September 2018

The functional significance of cell clusters in the notochordal nucleus pulposus: survival and signaling in the canine intervertebral disc.

1 reference

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4 September 2018

An improved staining method for intervertebral disc tissue.

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4 September 2018

Developmental biology. Making head or tail of Dickkopf.

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4 September 2018

Intermediate filament typing of the human embryonic and fetal notochord.

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4 September 2018

Notochordal Cell Produce and Assemble Extracellular Matrix in a Distinct Manner, Which May Be Responsible for the Maintenance of Healthy Nucleus Pulposus

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4 December 2018

Morphologic and morphometric magnetic resonance imaging features of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shape and orientation of articular facets of cervical vertebrae (C3-C7) in dogs denoting axial rotational ability: an osteological study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of nucleotomy on lumbar spine mechanics in compression and shear loading

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low back pain in relation to lumbar disc degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical properties of lumbar spinal motion segments as affected by partial disc removal

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of mesenchymal stromal cells from human degenerated nucleus pulposus: comparison with bone marrow mesenchymal stromal cells from the same subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Pathologic-Anatomical Study on Disc Degeneration in Dog: With Special Reference to the So-Called Enchondrosis Intervertebralis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnetic resonance imaging of articular process joint geometry and intervertebral disk degeneration in the caudal lumbar spine (L5-S1) of dogs with clinical signs of cauda equina compression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canonical Wnt signaling in the notochordal cell is upregulated in early intervertebral disk degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-specific targeting of caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facet joint geometry and intervertebral disk degeneration in the L5-S1 region of the vertebral column in German Shepherd dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23360510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23360510%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23360510%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23360510%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

ResearchGate publication ID

0 references

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