(Q36908418)

17 August 2017

1 reference

title

HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination (English)

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17 August 2017

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protein ubiquitination

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Boyault C

1

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17 August 2017

Sadoul K

series ordinal

2

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17 August 2017

Pabion M

series ordinal

3

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17 August 2017

Khochbin S

series ordinal

4

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17 August 2017

language of work or name

English

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publication date

1 August 2007

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17 August 2017

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17 August 2017

26

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17 August 2017

5468-5476

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17 August 2017

37

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210614

17 August 2017

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cites work

A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Assembly and mechanosensory function of focal adhesions: experiments and models.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC6-p97/VCP controlled polyubiquitin chain turnover

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

The viral control of cellular acetylation signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

A novel action of histone deacetylase inhibitors in a protein aggresome disease model.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Lysine 3 acetylation regulates the phosphorylation of yeast 6-phosphofructo-2-kinase under hypo-osmotic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Isolation and characterization of a novel class II histone deacetylase, HDAC10

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

p300 Transcriptional Repression Is Mediated by SUMO Modification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Acetylation and deacetylation of non-histone proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Three proteins define a class of human histone deacetylases related to yeast Hda1p

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Molecular cloning and characterization of a novel histone deacetylase HDAC10

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylase is a target of valproic acid-mediated cellular differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Basic research for hormone-sensitivity of breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC6 is a microtubule-associated deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Isolation and characterization of mammalian HDAC10, a novel histone deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Acetylation: a regulatory modification to rival phosphorylation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

RhoA/ROCK activation by growth hormone abrogates p300/histone deacetylase 6 repression of Stat5-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Farnesyltransferase inhibitors reverse taxane resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Mechanism of actin-based motility.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Cellular motility driven by assembly and disassembly of actin filaments

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Microtubule acetylation promotes kinesin-1 binding and transport.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Endoplasmic reticulum-associated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

An acetylation site in the middle domain of Hsp90 regulates chaperone function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Acetylation of histones and transcription-related factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Lysine acetylation and the bromodomain: a new partnership for signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Class II histone deacetylases: from sequence to function, regulation, and clinical implication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Prediction of prognosis of estrogen receptor-positive breast cancer with combination of selected estrogen-regulated genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Two catalytic domains are required for protein deacetylation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

HDAC6 expression is correlated with better survival in breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Characterization of the two catalytic domains in histone deacetylase 6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210614

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210614

1 reference

17 August 2017

1 reference