(Q36911415)

17 August 2017

1 reference

title

Sirtuins: the 'magnificent seven', function, metabolism and longevity (English)

1 reference

17 August 2017

6

Johan Auwerx

0 references

Kristina Schoonjans

series ordinal

5

object named as

Kristina Schoonjans

0 references

Christian Koehl

series ordinal

4

object named as

Christian Koehl

1 reference

17 August 2017

2

Marie Lagouge

1 reference

17 August 2017

Nassim Dali-Youcef

1

1 reference

PubMed ID

17701476

17 August 2017

Sébastien Froelich

series ordinal

3

1 reference

PubMed ID

17701476

17 August 2017

language of work or name

English

0 references

publication date

1 January 2007

1 reference

17 August 2017

1 reference

17 August 2017

39

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17 August 2017

5

1 reference

17 August 2017

335-345

1 reference

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

17 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Cloning and characterization of four SIR genes of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Mechanism of transcriptional silencing in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Calorie restriction, SIRT1 and metabolism: understanding longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Stoichiometry and compartmentation of NADH metabolism inSaccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Calorie restriction extends yeast life span by lowering the level of NADH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

HST2 mediates SIR2-independent life-span extension by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

The Ras and Sch9 pathways regulate stress resistance and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Regulation of longevity and stress resistance by Sch9 in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Alternate metabolism during the dauer stage of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Long-lived Drosophila with overexpressed dFOXO in adult fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Extended longevity in mice lacking the insulin receptor in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

PPAR(gamma) and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Characterization of a bidirectional promoter shared between two human genes related to aging: SIRT3 and PSMD13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Epigenetic silencing of RNA polymerase I transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701408194

10.1080/07853890701408194

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17701476