(Q36913094)

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Oxygen sensing and hypoxia-induced responses

scientific article published on January 2007

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Europe PubMed Central

17 August 2017

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Europe PubMed Central

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Oxygen sensing and hypoxia-induced responses (English)

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Europe PubMed Central

17 August 2017

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Peter J Ratcliffe

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Mathew L Coleman

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Mathew L Coleman

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Europe PubMed Central

17 August 2017

1 January 2007

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Europe PubMed Central

17 August 2017

Essays in Biochemistry

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stated in

Europe PubMed Central

17 August 2017

43

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Europe PubMed Central

17 August 2017

1-15

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stated in

Europe PubMed Central

17 August 2017

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

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Induction of SM-20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase-dependent cell death

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Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins

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Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

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Inhibition of NGF deprivation-induced death by low oxygen involves suppression of BIMEL and activation of HIF-1

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

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Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

1 reference

12 October 2022

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

1 reference

12 October 2022

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Targeting HIF-1 for cancer therapy

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Proline hydroxylation and gene expression

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Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

1 reference

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

1 reference

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Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

1 reference

12 October 2022

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Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

1 reference

12 October 2022

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Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment

1 reference

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The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

1 reference

12 October 2022

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Oxygen sensing by HIF hydroxylases

1 reference

12 October 2022

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The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin

1 reference

12 October 2022

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Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation

1 reference

12 October 2022

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JmjC-domain-containing proteins and histone demethylation

1 reference

12 October 2022

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Drosophila cyclin D/Cdk4 requires Hif-1 prolyl hydroxylase to drive cell growth

1 reference

12 October 2022

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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay

1 reference

12 October 2022

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Mammalian EGLN genes have distinct patterns of mRNA expression and regulation

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The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha

1 reference

12 October 2022

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Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

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12 October 2022

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The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3)

1 reference

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Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

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Signalling hypoxia by HIF hydroxylases

1 reference

12 October 2022

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A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

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Regulation of angiogenesis by hypoxia: role of the HIF system

1 reference

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Hypoxia signalling in cancer and approaches to enforce tumour regression

1 reference

12 October 2022

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Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

1 reference

12 October 2022

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

1 reference

12 October 2022

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ROS: really involved in oxygen sensing

1 reference

12 October 2022

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Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

1 reference

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Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

1 reference

12 October 2022

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Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer

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An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity.

1 reference

12 October 2022

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HIF-1 in cell cycle regulation, apoptosis, and tumor progression

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Inhibition of the catalytic activity of hypoxia-inducible factor-1alpha-prolyl-hydroxylase 2 by a MYND-type zinc finger

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

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Identifiers

DOI

10.1042/BSE0430001

1 reference

stated in

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

PubMed ID

17705789

retrieved

17 August 2017

ResearchGate publication ID

6133644

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(Q36913094)

Oxygen sensing and hypoxia-induced responses

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