(Q36913236)

17 August 2017

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title

The role of DNA repair in chronic lymphocytic leukemia pathogenesis and chemotherapy resistance (English)

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chronic lymphocytic leukemia

17 August 2017

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2

William Plunkett

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17 August 2017

Deepa Sampath

1

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17 August 2017

1 September 2007

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17 August 2017

Current Oncology Reports

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17 August 2017

9

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17 August 2017

5

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17 August 2017

361-367

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https://scigraph.springernature.com/pub.10.1007/s11912-007-0048-6

17 August 2017

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cites work

DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11912-007-0048-6

The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy.

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS11912-007-0048-6

Chlorambucil in indolent chronic lymphocytic leukemia. French Cooperative Group on Chronic Lymphocytic Leukemia

21 January 2018

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12 December 2020

Cladribine with cyclophosphamide and prednisone in the management of low-grade lymphoproliferative malignancies

1 reference

12 December 2020

Transcription by RNA polymerase II: a process linked to DNA repair.

1 reference

12 December 2020

Fludarabine increases oxaliplatin cytotoxicity in normal and chronic lymphocytic leukemia lymphocytes by suppressing interstrand DNA crosslink removal

1 reference

12 December 2020

Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia

1 reference

12 December 2020

Imatinib sensitizes CLL lymphocytes to chlorambucil

1 reference

12 December 2020

Combination chemotherapy of advanced chronic lymphocytic leukemia: the M-2 protocol (vincristine, BCNU, cyclophosphamide, melphalan, and prednisone).

1 reference

12 December 2020

Chromatin remodeling and repair of DNA double-strand breaks

1 reference

12 December 2020

DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells

1 reference

12 December 2020

Mechanism of action of purine analogues in chronic lymphocytic leukaemia

1 reference

12 December 2020

Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488.

1 reference

12 December 2020

Sequential cis-platinum and fludarabine with or without arabinosyl cytosine in patients failing prior fludarabine therapy for chronic lymphocytic leukemia: a phase II study

1 reference

12 December 2020

DNA repair enzyme expression in chronic lymphocytic leukemia vis-à-vis nitrogen mustard drug resistance

1 reference

12 December 2020

Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-yl)-benzo[h]chomen-4-one (NU7026)-mediated inhibition of DNA double-strand break repair via inhibition of DNA-dependent protein kinase

1 reference

12 December 2020

A retrospective comparison of three sequential groups of patients with Recurrent/Refractory chronic lymphocytic leukemia treated with fludarabine-based regimens

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12 December 2020

Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture

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12 December 2020

Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

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12 December 2020

Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway.

1 reference

12 December 2020

The controlling role of ATM in homologous recombinational repair of DNA damage

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12 December 2020

DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine

1 reference

12 December 2020

DNA repair: enzymatic mechanisms and relevance to drug response

1 reference

12 December 2020

Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia

1 reference

12 December 2020

New agents in chronic lymphocytic leukemia

1 reference

12 December 2020

Activation of a p53-mediated apoptotic pathway in quiescent lymphocytes after the inhibition of DNA repair by fludarabine

1 reference

12 December 2020

Efficacy of bendamustine in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase I/II study of the German CLL Study Group

1 reference

12 December 2020

Does cyclophosphamide (CPM) improve survival rates in patients with solid tumors?

1 reference

12 December 2020

Fludarabine, cyclophosphamide, and rituximab for the treatment of patients with chronic lymphocytic leukemia or indolent non-Hodgkin lymphoma.

1 reference

12 December 2020

DNA damage and the DNA-activated protein kinase

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12 December 2020

2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes

1 reference

12 December 2020

Pentostatin and cyclophosphamide: an effective new regimen in previously treated patients with chronic lymphocytic leukemia

1 reference

12 December 2020

Phase II study of fludarabine, cytarabine (Ara-C), cyclophosphamide, cisplatin and GM-CSF (FACPGM) in patients with Richter's syndrome or refractory lymphoproliferative disorders

1 reference

12 December 2020

Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents.

1 reference

12 December 2020

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

1 reference

12 December 2020

The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro

1 reference

12 December 2020

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

1 reference

12 December 2020

Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia

1 reference

12 December 2020

Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes

1 reference

12 December 2020

DNA repair activity in protein extracts of fresh human malignant lymphoid cells.

1 reference

12 December 2020

Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997.

1 reference

12 December 2020

Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia

1 reference

12 December 2020

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

1 reference

12 December 2020

Fludarabine plus cyclophosphamide is an efficient treatment for advanced chronic lymphocytic leukaemia (CLL): results of a phase II study of the German CLL Study Group

1 reference

12 December 2020

Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells

1 reference

12 December 2020

Pathways of DNA double-strand break repair during the mammalian cell cycle

1 reference

12 December 2020

Chlorambucil induction of HsRad51 in B-cell chronic lymphocytic leukemia

1 reference

12 December 2020

Results of the fludarabine and cyclophosphamide combination regimen in chronic lymphocytic leukemia

1 reference

12 December 2020

Primer RNA chain termination induced by 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-triphosphate. A mechanism of DNA synthesis inhibition

1 reference

12 December 2020

Richter's transformation in chronic lymphocytic leukemia

1 reference

12 December 2020

2-Chlorodeoxyadenosine alone and in combination with cyclophosphamide and mitoxantrone induce apoptosis in B chronic lymphocytic leukemia cells in vivo

1 reference

12 December 2020

Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event

1 reference

12 December 2020

Repair of DNA double strand breaks by non-homologous end joining

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12 December 2020

Homologous recombinational repair vis-à-vis chlorambucil resistance in chronic lymphocytic leukemia

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12 December 2020

Oxaliplatin-induced damage of cellular DNA

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12 December 2020

Repair of cisplatin--DNA adducts by the mammalian excision nuclease

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12 December 2020

Oxaliplatin: mechanism of action and antineoplastic activity

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12 December 2020

Efficacy and safety of fludarabine and cyclophosphamide combined therapy in patients with refractory/recurrent B-cell chronic lymphocytic leukaemia (B-CLL)-Polish multicentre study

1 reference

12 December 2020

Treatment of chronic lymphocytic leukemia

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12 December 2020

Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL.

1 reference

12 December 2020

The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks

1 reference

12 December 2020

Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia

1 reference

12 December 2020

Antitumor activity of oxaliplatin in combination with 5-fluorouracil and the thymidylate synthase inhibitor AG337 in human colon, breast and ovarian cancers.

1 reference

12 December 2020

Xrcc3 induces cisplatin resistance by stimulation of Rad51-related recombinational repair, S-phase checkpoint activation, and reduced apoptosis

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12 December 2020

Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (

1 reference

12 December 2020

10.1007/S11912-007-0048-6

Identifiers

DOI

1 reference

17 August 2017

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PubMed ID

17706164