(Q36914843)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

The continuing challenge of understanding, preventing, and treating neural tube defects (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Richard H. Finnell

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1

John B Wallingford

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Gary M Shaw

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

English

0 references

publication date

1 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

1222002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

6123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice

24 February 2020

cites work

1 reference

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How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals

29 September 2017

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In toto live imaging of mouse morphogenesis and new insights into neural tube closure

29 September 2017

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The role of primary cilia in the pathophysiology of neural tube defects

29 September 2017

1 reference

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A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

29 September 2017

1 reference

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Planar cell polarity and the developmental control of cell behavior in vertebrate embryos

29 September 2017

1 reference

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Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome

29 September 2017

1 reference

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Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome

29 September 2017

1 reference

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Cilia in vertebrate development and disease

29 September 2017

1 reference

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Self-formation of functional adenohypophysis in three-dimensional culture.

29 September 2017

1 reference

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Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans

29 September 2017

1 reference

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Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.

29 September 2017

1 reference

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A sustained dietary change increases epigenetic variation in isogenic mice

29 September 2017

1 reference

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Self-organizing optic-cup morphogenesis in three-dimensional culture

29 September 2017

1 reference

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ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

29 September 2017

1 reference

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A randomized trial of prenatal versus postnatal repair of myelomeningocele

29 September 2017

1 reference

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Association of retinoic acid receptor genes with meningomyelocele

29 September 2017

1 reference

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Molecular genetics and pathogenic mechanisms for the severe ciliopathies: insights into neurodevelopment and pathogenesis of neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Functional interactions between the LRP6 WNT co-receptor and folate supplementation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Maternal and neonatal serum zinc level and its relationship with neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Folic acid in early pregnancy: a public health success story

29 September 2017

1 reference

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Dynamic imaging of mammalian neural tube closure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

The relationship between sonic Hedgehog signaling, cilia, and neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

The cognitive phenotype of spina bifida meningomyelocele

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Epidemiologic and genetic aspects of spina bifida and other neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

The primary cilium: a signalling centre during vertebrate development

29 September 2017

1 reference

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Genetics and development of neural tube defects.

29 September 2017

1 reference

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Effect of supplemental folic acid in pregnancy on childhood asthma: a prospective birth cohort study.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development

29 September 2017

1 reference

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118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

29 September 2017

1 reference

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The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects.

29 September 2017

1 reference

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Insights into prevention of human neural tube defects by folic acid arising from consideration of mouse mutants

29 September 2017

1 reference

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Neural tube defects and maternal folate intake among pregnancies conceived after folic acid fortification in the United States

29 September 2017

1 reference

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In utero supplementation with methyl donors enhances allergic airway disease in mice

29 September 2017

1 reference

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Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.

29 September 2017

1 reference

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Mutations in VANGL1 associated with neural-tube defects

29 September 2017

1 reference

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Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Neural tube defects and folate: case far from closed

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Neural tube closure and neural tube defects: studies in animal models reveal known knowns and known unknowns

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Hedgehog signalling in the mouse requires intraflagellar transport proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Neural tube closure requires Dishevelled-dependent convergent extension of the midline

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Screening for neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Towards a cellular and molecular understanding of neurulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Spina bifida outcome: a 25-year prospective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Expression of the sonic hedgehog gene in human embryos with neural tube defects

29 September 2017

1 reference

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Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Mena is required for neurulation and commissure formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Essential roles for the Abl and Arg tyrosine kinases in neurulation

29 September 2017

1 reference

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Neural tube closure in the chick embryo is multiphasic

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Teratogen update: valproic acid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Cell movements of the deep layer of non-neural ectoderm underlie complete neural tube closure in Xenopus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

The emerging role of epigenetic mechanisms in the etiology of neural tube defects

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Enabled (Xena) regulates neural plate morphogenesis, apical constriction, and cellular adhesion required for neural tube closure in Xenopus

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Can terathanasia explain the protective effect of folic-acid supplementation on birth defects?

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Effect of multifactorial genetic liability to exencephaly on the teratogenic effect of valproic acid in mice.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Hypothesis: the female excess in cranial neural tube defects reflects an epigenetic drag of the inactivating X chromosome on the molecular mechanisms of neural fold elevation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Folic acid use in pregnancy and the development of atopy, asthma, and lung function in childhood.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Polymorphisms in DNA repair genes as risk factors for spina bifida and orofacial clefts.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Shroom induces apical constriction and is required for hingepoint formation during neural tube closure

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Maternal diabetes mellitus and infant malformations

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Sonic hedgehog and the molecular regulation of mouse neural tube closure.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension: parallel forces elongating the body axis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Inositol prevents folate-resistant neural tube defects in the mouse.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Risk of neural tube defect-affected pregnancies among obese women

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677196

Extremely high prevalence of neural tube defects in a 4-county area in Shanxi Province, China.

4 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Are obese women at higher risk for producing malformed offspring?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Prepregnant weight in relation to risk of neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Effects of hyperinsulinemia and obesity on risk of neural tube defects among Mexican Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

In utero antiepileptic drug exposure: fetal death and malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Folic acid prevents exencephaly in Cited2 deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Fetal surgery for myelomeningocele: trials and tribulations. Isabella Forshall Lecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Changes in the birth prevalence of selected birth defects after grain fortification with folic acid in the United States: findings from a multi-state population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Reduction in Neural-Tube Defects after Folic Acid Fortification in Canada

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

The National Birth Defects Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Shroom family proteins regulate gamma-tubulin distribution and microtubule architecture during epithelial cell shape change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222002

Neural tube defect surveillance and folic acid intervention--Texas-Mexico border, 1993-1998

21 January 2018

1 reference

12 December 2020

Multistep role for actin in initial closure of the mesencephalic neural groove in the chick embryo

1 reference

12 December 2020

Study of the vertebral column in human craniorhachischisis. The significance of the notochordal alterations

1 reference

12 December 2020

Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1222002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

release_vi4nsomb2zat7gszlftaxzy3qu

24 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vi4nsomb2zat7gszlftaxzy3qu

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23449594%20AND%20SRC:MED&resulttype=core&format=json