(Q36926122)

English

Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine

scientific article published on 07 May 2008

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine (English)

1 reference

Europe PubMed Central

17 August 2017

1 reference

based on heuristic

inferred from title

Maria Almira Correia

5

object named as

Maria Almira Correia

1 reference

Europe PubMed Central

17 August 2017

author name string

Robin E Pearce

1

1 reference

Europe PubMed Central

17 August 2017

Wei Lu

2

1 reference

Europe PubMed Central

17 August 2017

Yongqiang Wang

3

1 reference

Europe PubMed Central

17 August 2017

Jack P Uetrecht

4

1 reference

Europe PubMed Central

17 August 2017

J Steven Leeder

6

1 reference

Europe PubMed Central

17 August 2017

publication date

7 May 2008

1 reference

Europe PubMed Central

17 August 2017

Drug Metabolism and Disposition

1 reference

Europe PubMed Central

17 August 2017

36

1 reference

Europe PubMed Central

17 August 2017

8

1 reference

Europe PubMed Central

17 August 2017

1637-1649

1 reference

Europe PubMed Central

17 August 2017

CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

29 September 2017

Some properties of purified isocitric enzyme

1 reference

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29 September 2017

Genetic contribution to variable human CYP3A-mediated metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

29 September 2017

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

29 September 2017

Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

29 September 2017

Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs

1 reference

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29 September 2017

Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study

1 reference

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Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis.

1 reference

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29 September 2017

Epitope mapping studies with human anti-cytochrome P450 3A antibodies.

1 reference

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29 September 2017

Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk

1 reference

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29 September 2017

Drug disposition and drug hypersensitivity

1 reference

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29 September 2017

The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

29 September 2017

Expression of autoantibodies to specific cytochromes P450 in a case of disulfiram hepatitis.

1 reference

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27 June 2018

Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

27 June 2018

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

27 June 2018

Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

27 June 2018

Metabolism of carbamazepine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

27 June 2018

Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

27 June 2018

P450 2C18 catalyzes the metabolic bioactivation of phenytoin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Human in vitro glutathionyl and protein adducts of carbamazepine-10,11-epoxide, a stable and pharmacologically active metabolite of carbamazepine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Pathways of carbamazepine bioactivation in vitro: II. The role of human cytochrome P450 enzymes in the formation of 2-hydroxyiminostilbene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Inhibition and activation of the human liver microsomal and human cytochrome P450 3A4 metabolism of testosterone by deployment-related chemicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Bioactivation of tamoxifen by recombinant human cytochrome p450 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Autoantibodies against cytochrome P450s in sera of children treated with immunosuppressive drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Differential selectivity in carbamazepine-induced inactivation of cytochrome P450 enzymes in rat and human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Fatal hepatitis associated with isoflurane exposure and CYP2A6 autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Free radical intermediates of phenytoin and related teratogens. Prostaglandin H synthase-catalyzed bioactivation, electron paramagnetic resonance spectrometry, and photochemical product analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562787

4 September 2018

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

1 reference

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4 September 2018

Anticonvulsant toxicity in vitro: possible role of arene oxides

1 reference

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4 September 2018

Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

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inferred from PubMed ID database lookup

Interactions of dihydralazine with cytochromes P4501A: a possible explanation for the appearance of anti-cytochrome P4501A2 autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Covalent binding of carbamazepine oxidative metabolites to neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-reactive metabolites of carbamazepine in mouse liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tienilic acid-induced autoimmune hepatitis: anti-liver and-kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of 2-hydroxyiminostilbene in the urine of patients taking carbamazepine and its oxidation to a reactive iminoquinone intermediate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies against cytochromes P-4502E1 and P-4503A in alcoholics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18463198

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/DMD.107.019562

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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