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Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic.
scientific article published on 02 May 2013
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Europe PubMed Central
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3682529
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
title
Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic
(English)
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PMC publication ID
3682529
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
author
Michael Carpenter
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3
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Europe PubMed Central
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3682529
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29 February 2020
Lela Lackey
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4
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Europe PubMed Central
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3682529
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
Reuben S Harris
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Reuben S Harris
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3682529
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29 February 2020
William L Brown
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William L Brown
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3682529
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29 February 2020
author name string
Allison M Land
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1
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Europe PubMed Central
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3682529
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
Emily K Law
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2
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Europe PubMed Central
PMC publication ID
3682529
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29 February 2020
language of work or name
English
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publication date
2 May 2013
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Europe PubMed Central
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3682529
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29 February 2020
published in
Journal of Biological Chemistry
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3682529
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29 February 2020
volume
288
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Europe PubMed Central
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3682529
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29 February 2020
issue
24
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Europe PubMed Central
PMC publication ID
3682529
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29 February 2020
page(s)
17253-17260
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3682529
reference URL
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29 February 2020
cites work
APOBEC3B is an enzymatic source of mutation in breast cancer.
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29 September 2017
APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells.
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29 September 2017
Systematic identification of functional residues in mammalian histone H2AX
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29 September 2017
Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A
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29 September 2017
Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G.
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29 September 2017
APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1
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29 September 2017
APOBEC3B and AID have similar nuclear import mechanisms
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29 September 2017
Protective and pathogenic functions of macrophage subsets
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29 September 2017
APOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.
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29 September 2017
Target cell-mediated editing of HIV-1 cDNA by APOBEC3 proteins in human macrophages.
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29 September 2017
Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1
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29 September 2017
Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response
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Monoubiquitination of H2AX protein regulates DNA damage response signaling
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29 September 2017
APOBEC3A can activate the DNA damage response and cause cell-cycle arrest
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism
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29 September 2017
Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms
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PubMed Central
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29 September 2017
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction
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29 September 2017
Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes
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29 September 2017
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
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PubMed Central
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29 September 2017
APOBEC3 proteins inhibit LINE-1 retrotransposition in the absence of ORF1p binding
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Two regions within the amino-terminal half of APOBEC3G cooperate to determine cytoplasmic localization
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PubMed Central
reference URL
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29 September 2017
Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions
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29 September 2017
Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins
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PubMed Central
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29 September 2017
Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding.
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29 September 2017
Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism
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PubMed Central
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29 September 2017
Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity
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29 September 2017
Differential inhibition of long interspersed element 1 by APOBEC3 does not correlate with high-molecular-mass-complex formation or P-body association
1 reference
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PubMed Central
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29 September 2017
All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition
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PubMed Central
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29 September 2017
Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
APOBEC3 proteins inhibit human LINE-1 retrotransposition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
29 September 2017
Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
29 September 2017
Cytidine deamination of retroviral DNA by diverse APOBEC proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
29 September 2017
Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
29 September 2017
Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
29 September 2017
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
29 September 2017
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Mouse NIPK interacts with ATF4 and affects its transcriptional activity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
SINK Is a p65-interacting Negative Regulator of NF-κB-dependent Transcription
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Megabase chromatin domains involved in DNA double-strand breaks in vivo
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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29 September 2017
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.
1 reference
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PubMed Central
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27 June 2018
Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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27 June 2018
APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
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27 June 2018
Active nuclear import and cytoplasmic retention of activation-induced deaminase
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682529
retrieved
4 September 2018
Identifiers
DOI
10.1074/JBC.M113.458661
1 reference
stated in
Europe PubMed Central
PMC publication ID
3682529
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PMC publication ID
3682529
1 reference
stated in
Europe PubMed Central
PMC publication ID
3682529
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed publication ID
23640892
1 reference
stated in
Europe PubMed Central
PMC publication ID
3682529
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23640892%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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