(Q36959438)

17 August 2017

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title

Androgen-response elements in hormone-refractory prostate cancer: implications for treatment development (English)

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17 August 2017

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2

Eric J Small

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17 August 2017

Andrew C Hsieh

1

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17 August 2017

Charles J Ryan

series ordinal

3

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17 August 2017

publication date

1 October 2007

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Lancet Oncology Commission

17 August 2017

published in

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17 August 2017

volume

8

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17 August 2017

issue

10

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17 August 2017

page(s)

933-939

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Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance

17 August 2017

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cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cells

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7 January 2021

Genomics of prostate cancer: is there anything to "translate"?

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Molecular determinants of resistance to antiandrogen therapy

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7 January 2021

Mutation of the androgen receptor causes oncogenic transformation of the prostate

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7 January 2021

Ligand-independent androgen receptor activity is activation function-2-independent and resistant to antiandrogens in androgen refractory prostate cancer cells

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7 January 2021

Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells

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7 January 2021

The development of androgen-independent prostate cancer

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7 January 2021

The androgen axis in recurrent prostate cancer

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7 January 2021

Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer

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7 January 2021

Selective DNA binding by the androgen receptor as a mechanism for hormone-specific gene regulation

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7 January 2021

The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences

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7 January 2021

The role of DNA response elements as allosteric modulators of steroid receptor function

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7 January 2021

Coordinate regulation of lipogenic gene expression by androgens: evidence for a cascade mechanism involving sterol regulatory element binding proteins

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7 January 2021

Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway

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7 January 2021

SREBP transcription factors: master regulators of lipid homeostasis

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7 January 2021

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

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7 January 2021

Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor

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7 January 2021

Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence

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7 January 2021

Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2.

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7 January 2021

Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

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7 January 2021

Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).

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7 January 2021

Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis

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7 January 2021

Inhibition of death receptor signals by cellular FLIP

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7 January 2021

The androgen receptor directly targets the cellular Fas/FasL-associated death domain protein-like inhibitory protein gene to promote the androgen-independent growth of prostate cancer cells

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7 January 2021

Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Androgen receptor and prostate apoptosis response factor-4 target the c-FLIP gene to determine survival and apoptosis in the prostate gland

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Targeting the short form of cFLIP by RNA interference is sufficient to enhance TRAIL sensitivity in PC3 prostate carcinoma cells

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis

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7 January 2021

Doxorubicin pretreatment sensitizes prostate cancer cell lines to TRAIL induced apoptosis which correlates with the loss of c-FLIP expression

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Doxorubicin increases the effectiveness of Apo2L/TRAIL for tumor growth inhibition of prostate cancer xenografts

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7 January 2021

The anticancer drug mithramycin A sensitises tumour cells to apoptosis induced by tumour necrosis factor (TNF).

1 reference

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7 January 2021

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation

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7 January 2021

Identification of a novel functional androgen response element within hPar1 promoter: implications to prostate cancer progression

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7 January 2021

Thrombin receptor expression is upregulated in prostate cancer.

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7 January 2021

Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation

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7 January 2021

PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism

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7 January 2021

Incidence of cancer after prophylaxis with warfarin against recurrent venous thromboembolism. Duration of Anticoagulation Trial

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7 January 2021

Thrombin generation and the pathogenesis of cancer

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7 January 2021

The role of fibroblast growth factors and their receptors in prostate cancer.

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7 January 2021

Regulation of FGF8 expression by the androgen receptor in human prostate cancer

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7 January 2021

FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease

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7 January 2021

FGF8 isoform b expression in human prostate cancer

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7 January 2021

Smart drugs in prostate cancer

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7 January 2021

Adenovirus-mediated expression of a soluble fibroblast growth factor receptor inhibits in vitro growth of prostate DU145 cells

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Relationship of p21(WAF-I) protein expression with prognosis in advanced prostate cancer treated by androgen ablation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Expression of p21 cell cycle protein is an independent predictor of response to salvage radiotherapy after radical prostatectomy

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

The growth inhibitory effect of p21 adenovirus on androgen-dependent and -independent human prostate cancer cells

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Gene expression correlates of clinical prostate cancer behavior

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Epithelial-restricted gene profile of primary cultures from human prostate tumors: a molecular approach to predict clinical behavior of prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970316-9

7 January 2021

Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators.

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7 January 2021

10.1016/S1470-2045(07)70316-9

Identifiers

DOI

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17 August 2017

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