(Q36966213)

English

Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43

scientific article published on 21 March 2013

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43 (English)

1 reference

Europe PubMed Central

17 August 2017

Burkholderia thailandensis

1 reference

Thailanstatin C

1 reference

Thailanstatin A

1 reference

Thailanstatin B

1 reference

1 reference

author name string

Xiangyang Liu

1

1 reference

Europe PubMed Central

17 August 2017

Sreya Biswas

2

1 reference

Europe PubMed Central

17 August 2017

Michael G Berg

3

1 reference

Europe PubMed Central

17 August 2017

Christopher M Antapli

4

1 reference

Europe PubMed Central

17 August 2017

Feng Xie

5

1 reference

Europe PubMed Central

17 August 2017

Qi Wang

6

1 reference

Europe PubMed Central

17 August 2017

Man-Cheng Tang

7

1 reference

Europe PubMed Central

17 August 2017

Gong-Li Tang

8

1 reference

Europe PubMed Central

17 August 2017

Lixin Zhang

9

1 reference

Europe PubMed Central

17 August 2017

Gideon Dreyfuss

10

1 reference

Europe PubMed Central

17 August 2017

Yi-Qiang Cheng

11

1 reference

Europe PubMed Central

17 August 2017

language of work or name

0 references

publication date

21 March 2013

1 reference

Europe PubMed Central

17 August 2017

full work available at URL

https://europepmc.org/articles/pmc3696399?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np300913h?email=unpaywall_01@example.com

Journal of Natural Products

1 reference

Europe PubMed Central

17 August 2017

76

1 reference

Europe PubMed Central

17 August 2017

4

1 reference

Europe PubMed Central

17 August 2017

685-693

1 reference

Europe PubMed Central

17 August 2017

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np300913h?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

Bioactive natural products from Lysobacter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Revised genome sequence of Burkholderia thailandensis MSMB43 with improved annotation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Genome-based bioprospecting of microbes for new therapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Alternative splicing interference by xenobiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Biological validation that SF3b is a target of the antitumor macrolide pladienolide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Histone deacetylase inhibitors from Burkholderia thailandensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

High-redundancy draft sequencing of 15 clinical and environmental Burkholderia strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Expansion of the eukaryotic proteome by alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Genomics of secondary metabolite production by Pseudomonas spp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Entomopathogenic bacteria as a source of secondary metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

RNA and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Alternative isoform regulation in human tissue transcriptomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Recovery of a Burkholderia thailandensis-like isolate from an Australian water source

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Halogenation strategies in natural product biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Chromobacterium violaceum: a review of pharmacological and industiral perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

The Y14 protein communicates to the cytoplasm the position of exon-exon junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

29 September 2017

Discovery and activity profiling of thailandepsins A through F, potent histone deacetylase inhibitors, from Burkholderia thailandensis E264.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

27 June 2018

FK228 from Burkholderia thailandensis MSMB43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

27 June 2018

Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

27 June 2018

Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

27 June 2018

New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

27 June 2018

Genomics-driven discovery of burkholderic acid, a noncanonical, cryptic polyketide from human pathogenic Burkholderia species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Cloning and elucidation of the FR901464 gene cluster revealing a complex acyltransferase-less polyketide synthase using glycerate as starter units.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Catalytic promiscuity of halohydrin dehalogenase and its application in enantioselective epoxide ring opening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

TLC fractionation and visualization of selected phenolic compounds applied as drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696399

4 September 2018

Preparation of efficient splicing extracts from whole cells, nuclei, and cytoplasmic fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23517093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465

1 reference

https://pubmed.ncbi.nlm.nih.gov/23517093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mining microbial genomes for new natural products and biosynthetic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23517093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. II. Physico-chemical properties and structure elucidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23517093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FR901464: total synthesis, proof of structure, and evaluation of synthetic analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/23517093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/23517093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/NP300913H

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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