(Q36967364)

English

Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer.

scientific article published on 15 May 2013

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scholarly article

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1 March 2020

Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer (English)

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1 March 2020

apoptotic process

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10

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1 March 2020

author name string

Xiaolin Hu

1

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1 March 2020

Kankana Bardhan

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1 March 2020

Amy V Paschall

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1 March 2020

Dafeng Yang

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1 March 2020

Jennifer L Waller

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1 March 2020

Mary Anne Park

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1 March 2020

Asha Nayak-Kapoor

7

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1 March 2020

Thomas A Samuel

8

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1 March 2020

Scott I Abrams

9

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15 May 2013

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1 March 2020

Journal of Biological Chemistry

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1 March 2020

288

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1 March 2020

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1 March 2020

19103-19115

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1 March 2020

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner

1 reference

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Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.

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Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells.

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Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cells

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Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.

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Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice

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High cell surface death receptor expression determines type I versus type II signaling

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A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.

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Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice.

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TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696683

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1 reference

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Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL

1 reference

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29 September 2017

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1 reference

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1 reference

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Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells

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IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

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4 September 2018

CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/23677993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.434530

1 reference

Europe PubMed Central

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1 March 2020

1 reference

Europe PubMed Central

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1 March 2020

1 reference

Europe PubMed Central

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1 March 2020

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