(Q36968901)

17 August 2017

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title

The HIF/VHL pathway: from oxygen sensing to innate immunity (English)

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17 August 2017

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Naomi N McGovern

2

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Edwin R Chilvers

object named as

Edwin R Chilvers

series ordinal

4

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Sarah Walmsley

object named as

Sarah R Walmsley

series ordinal

1

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Moira K B Whyte

series ordinal

3

object named as

Moira K B Whyte

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17 August 2017

publication date

11 October 2007

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American Journal of Respiratory Cell and Molecular Biology

17 August 2017

published in

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17 August 2017

volume

38

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17 August 2017

issue

3

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17 August 2017

page(s)

251-255

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The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Isolation and characterization of the hypoxia-inducible factor 1beta in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Cloning of hif-1alpha and hif-2alpha and mRNA expression pattern during development in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Sensing and responding to hypoxia via HIF in model invertebrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

THE NATURE OF LEUKEMIC BLOOD CELLS AS DETERMINED BY THEIR METABOLISM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Hypoxia up-regulates triosephosphate isomerase expression via a HIF-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

HIF-1alpha is essential for myeloid cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

HIF-1alpha expression regulates the bactericidal capacity of phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

How Toll-like receptors signal: what we know and what we don't know

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Translational mini-review series on Toll-like receptors: networks regulated by Toll-like receptors mediate innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Genotype-phenotype correlations in von Hippel-Lindau disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Genotype-phenotype correlation in von Hippel-Lindau syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2007-0331TR

21 January 2018

Identifiers

DOI

10.1165/RCMB.2007-0331TR

1 reference

17 August 2017

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