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Hepatitis C virus (HCV): an RNA virus with a pro-oncogenic potential.
scientific article published on September 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Hepatitis C virus (HCV): an RNA virus with a pro-oncogenic potential
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
main subject
Hepatitis C virus
1 reference
based on heuristic
inferred from title
author
Anna Alisi
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author name string
Clara Balsano
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
publication date
1 September 2007
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
published in
Digestive and Liver Disease
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
volume
39 Suppl 1
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
page(s)
S46-51
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
cites work
Diagnosing hepatocellular carcinoma: a virtual reality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between chronic hepatitis C infection and hepatocellular carcinoma in a Scottish population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
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inferred from DOI database lookup
Viruses and tumours--an update
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
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inferred from DOI database lookup
HCV-Related Transformation and New Therapeutic Strategies: An Update
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
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inferred from DOI database lookup
Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
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inferred from DOI database lookup
The molecular virology of hepatitis C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural biology of hepatitis C virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the hepatitis C virus glycoproteins in infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient initiation of HCV RNA replication in cell culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus entry: potential receptors and their biological functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of transforming viruses on cellular mutagenesis, genome stability, and cellular transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatocellular carcinoma: an epidemiologic view
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of hepatitis C virus-associated hepatocarcinogenesis: lessons from animal model studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic instability and chromosomal instability in hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein: possible roles in viral pathogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclins: roles in mitogenic signaling and oncogenic transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitosis: a matter of getting rid of the right protein at the right time
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein regulates cell growth and signal transduction pathway transmitting growth stimuli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thr 446 phosphorylation of PKR by HCV core protein deregulates G2/M phase in HCC cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sustained activation of the Raf/MEK/Erk pathway in response to EGF in stable cell lines expressing the Hepatitis C Virus (HCV) core protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein induces cell proliferation and activates ERK, JNK, and p38 MAP kinases together with the MAP kinase phosphatase MKP-1 in a HepG2 Tet-Off cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HCV core protein modulates Rb pathway through pRb down-regulation and E2F-1 up-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p38 MAPK and RNA-dependent protein kinase (PKR) in hepatitis C virus core-dependent nuclear delocalization of cyclin B1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell transformation induced by hepatitis C virus NS3 serine protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of hepatitis C virus nonstructural protein NS3 on proliferation and MAPK phosphorylation of normal hepatocyte line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of c-Jun NH2-terminal kinase (JNK) signaling pathway is essential for the stimulation of hepatitis C virus (HCV) non-structural protein 3 (NS3)-mediated cell growth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations and aneuploidy: co-conspirators in cancer?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A tentative classification of centrosome abnormalities in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic mechanisms of hepatocarcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of hepatitis C virus NS5A protein induces chromosome instability via mitotic cell cycle dysregulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inherent increase of apoptosis in liver tumors: implications for carcinogenesis and tumor regression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HCV core protein acts as a positive regulator of fas-mediated apoptosis in a human lymphoblastoid T cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical and functional interaction between HCV core protein and the different p73 isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HCV NS5A abrogates p53 protein function by interfering with p53-DNA binding.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
To interfere and to anti-interfere: the interplay between hepatitis C virus and interferon.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targets and mechanisms for the regulation of translation in malignant transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiviral actions of interferons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stats: multifaceted regulators of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus NS5A protein interacts with 2',5'-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The oncogenic potential of hepatitis C virus NS5A sequence variants is associated with PKR regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus envelope protein E2 does not inhibit PKR by simple competition with autophosphorylation sites in the RNA-binding domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the interferon-inducible protein kinase PKR by hepatocellular carcinoma derived-hepatitis C virus core protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons from hereditary colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1590-8658%2807%2980010-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1590-8658(07)80010-7
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
PubMed ID
17936223
1 reference
stated in
Europe PubMed Central
PubMed ID
17936223
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17936223%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
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