(Q36006754)

11 August 2017

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title

Impact of transforming viruses on cellular mutagenesis, genome stability, and cellular transformation (English)

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11 August 2017

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Michael L Gatza

1

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11 August 2017

Chandtip Chandhasin

series ordinal

2

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11 August 2017

Razvan I Ducu

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3

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11 August 2017

Susan J Marriott

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4

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11 August 2017

1 March 2005

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Environmental and Molecular Mutagenesis

11 August 2017

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11 August 2017

45

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11 August 2017

2-3

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11 August 2017

304-325

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Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency

11 August 2017

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Attach first, then detach: a role for cyclin B-dependent kinase 1 in coordinating proteolysis with spindle assembly

21 January 2018

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An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300

21 January 2018

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Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B

21 January 2018

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Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells

21 January 2018

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21 January 2018

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Increased chromosomal alterations and micronuclei formation in human hepatoma HepG2 cells transfected with the hepatitis B virus HBX gene

21 January 2018

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Novel interactions between human T-cell leukemia virus type I Tax and activating transcription factor 3 at a cyclic AMP-responsive element

21 January 2018

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Molecular analysis of lacI mutations in Rat2 cells exposed to 7,12-dimethylbenz[a]anthracene: evidence for DNA sequence and DNA strand biases for mutation

21 January 2018

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D-type cyclin-dependent kinase activity in mammalian cells

21 January 2018

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Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb

21 January 2018

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In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax.

21 January 2018

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The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

21 January 2018

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Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

21 January 2018

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Efficient repair of bulky anti-BPDE DNA adducts from non-transcribed DNA strand requires functional p53 but not p21(waf1/cip1) and pRb.

21 January 2018

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Aberrant expression of the p53 tumor suppressor gene in adult T-cell leukemia and HTLV-I-infected cells

21 January 2018

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Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction

21 January 2018

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

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7 January 2021

Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.

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7 January 2021

Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway

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7 January 2021

No serological evidence for non-sexual spread of HPV16

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7 January 2021

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

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7 January 2021

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

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7 January 2021

HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration

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7 January 2021

Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factors

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7 January 2021

HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

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7 January 2021

Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo

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7 January 2021

Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements

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7 January 2021

Determinants of genital human papillomavirus infection in low-risk women in Portland, Oregon.

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7 January 2021

Hepatitis B virus X protein interferes with cellular DNA repair.

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7 January 2021

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls

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7 January 2021

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer

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7 January 2021

Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway

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7 January 2021

Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects

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7 January 2021

Human papillomavirus and cervical cancer

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7 January 2021

Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease

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7 January 2021

Functional and biochemical interaction of the HTLV-I Tax1 transactivator with TBP.

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7 January 2021

Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. American Social Health Association Panel

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7 January 2021

Epidemiological characteristics and risk factors of hepatocellular carcinoma

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7 January 2021

Shaping the nuclear action of NF-kappaB

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7 January 2021

Hepatitis B virus transmission and hepatocarcinogenesis: a 9 year retrospective cohort of 13676 relatives with hepatocellular carcinoma.

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7 January 2021

Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation

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7 January 2021

Phosphorylated CREB binds specifically to the nuclear protein CBP

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7 January 2021

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

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7 January 2021

Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases.

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7 January 2021

Overexpression of p21(waf1) in human T-cell lymphotropic virus type 1-infected cells and its association with cyclin A/cdk2.

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7 January 2021

X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway

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7 January 2021

Transgenic mice containing hepatitis B virus sequences are more susceptible to carcinogen-induced hepatocarcinogenesis

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7 January 2021

Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members

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7 January 2021

Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins

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7 January 2021

A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions

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7 January 2021

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

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7 January 2021

Association of skin malignancies with various and multiple carcinogenic and noncarcinogenic human papillomaviruses in renal transplant recipients

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7 January 2021

The absence of genital human papillomavirus DNA in virginal women

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7 January 2021

A genetic model for colorectal tumorigenesis

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7 January 2021

Human T-cell leukemia viruses: epidemiology, biology, and pathogenesis

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7 January 2021

Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

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7 January 2021

Activation of oncogenic transcription factor AP-1 in T cells infected with human T cell leukemia virus type 1.

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7 January 2021

Cytogenetic studies on the adult T-cell leukemia in Japan.

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7 January 2021

Chromosome 14 translocations in non-burkitt lymphomas

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7 January 2021

Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

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7 January 2021

Inactivation of hTERT transcription by Tax.

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7 January 2021

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

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7 January 2021

Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.

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7 January 2021

Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

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7 January 2021

Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

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7 January 2021

p300/CBP/p53 interaction and regulation of the p53 response

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7 January 2021

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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7 January 2021

Cervical-vaginal and intraanal human papillomavirus infection of young girls with external genital warts

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7 January 2021

Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L1 virus-like particle vaccine

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7 January 2021

Role of tumor suppressor genes in the development of adult T cell leukemia/lymphoma (ATLL).

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7 January 2021

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene.

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7 January 2021

A transgenic mouse model for human neurofibromatosis

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7 January 2021

Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element

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7 January 2021

SV40-transformed human fibroblasts exhibit a characteristic chromosomal pattern

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7 January 2021

Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma

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7 January 2021

Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis

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7 January 2021

Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1.

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7 January 2021

Cytogenetic studies of human T-cell leukemia virus type I carriers. A family study

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7 January 2021

Molecular mechanism of cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I.

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7 January 2021

Chromosome segregation and cancer: cutting through the mystery

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7 January 2021

HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene

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7 January 2021

Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival

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7 January 2021

HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity

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7 January 2021

Hepatitis B virus X protein inhibits nucleotide excision repair

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7 January 2021

Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

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7 January 2021

Human papillomavirus typing and the reduction of cervical cancer risk.

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7 January 2021

Molecular biology and pathogenesis of the human T-cell leukaemia/lymphotropic virus Type-1 (HTLV-1).

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7 January 2021

The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

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7 January 2021

NF-kappaB and cell-cycle regulation: the cyclin connection

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7 January 2021

Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitors

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7 January 2021

Characterization of primary human keratinocytes transformed by human papillomavirus type 18.

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7 January 2021

Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals

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7 January 2021

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

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7 January 2021

CREB/ATF-dependent repression of cyclin a by human T-cell leukemia virus type 1 Tax protein

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7 January 2021

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

Smoking, diet, pregnancy and oral contraceptive use as risk factors for cervical intra-epithelial neoplasia in relation to human papillomavirus infection

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7 January 2021

HBX causes cyclin D1 overexpression and development of breast cancer in transgenic animals that are heterozygous for p53.

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7 January 2021

Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts

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7 January 2021

Very high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic mice

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7 January 2021

Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene

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7 January 2021

Hepatocellular carcinoma in a hepatitis B 'x' transgenic mouse model: A sequential pathological evaluation

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7 January 2021

Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice

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7 January 2021

Differential activation of viral and cellular promoters by human T-cell lymphotropic virus-1 tax and cAMP-responsive element modulator isoforms

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7 January 2021

Hepatitis B virus X protein interacts with a probable cellular DNA repair protein

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7 January 2021

Transcriptional repression of the human p53 gene by hepatitis B viral X protein

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7 January 2021

Suppression of DNA repair by HTLV type 1 Tax correlates with Tax trans-activation of proliferating cell nuclear antigen gene expression

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7 January 2021

Accelerated G(1) phase progression induced by the human T cell leukemia virus type I (HTLV-I) Tax oncoprotein

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7 January 2021

Genomic instability driven by the human T-cell leukemia virus type I (HTLV-I) oncoprotein, Tax.

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7 January 2021

Genetic instabilities in human cancers

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7 January 2021

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.

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7 January 2021

Genetic alterations and oncogenic pathways in hepatocellular carcinoma.

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7 January 2021

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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7 January 2021

Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells.

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7 January 2021

Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a

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7 January 2021

Genetic characterization of immortalized human prostate epithelial cell cultures. Evidence for structural rearrangements of chromosome 8 and i(8q) chromosome formation in primary tumor-derived cells

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7 January 2021

Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice

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7 January 2021

Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein

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7 January 2021

Identification of kinetochores and DNA synthesis in micronuclei induced by mitomycin C and colchicine in Chinese hamster ovary cells

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7 January 2021

Induction of micronuclei by HTLV-I Tax: a cellular assay for function

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7 January 2021

Clastogenic effect of the human T-cell leukemia virus type I Tax oncoprotein correlates with unstabilized DNA breaks

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7 January 2021

Disruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin E

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7 January 2021

Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

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7 January 2021

Somatic rearrangement of chromosome 14 in human lymphocytes

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7 January 2021

Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p107.

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7 January 2021

Genetic deletion and human papillomavirus infection in cervical cancer: loss of heterozygosity sites at 3p and 5p are important genetic events

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7 January 2021

Trans-activator Tax of human T-cell leukemia virus type 1 enhances mutation frequency of the cellular genome

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7 January 2021

Adult T-cell leukemia. Chromosome analysis of 15 cases

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7 January 2021

Principles of CDK regulation

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7 January 2021

Human papillomavirus infection in sexually active adolescent females: prevalence and risk factors

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7 January 2021

The retinoblastoma gene family: cousins with overlapping interests.

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7 January 2021

Hepatitis B virus X protein: structure, function and biology.

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7 January 2021

Comprehensive allelotyping of human hepatocellular carcinoma

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7 January 2021

p16 promoter hypermethylation in human hepatocellular carcinoma with or without hepatitis virus infection

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7 January 2021

The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice

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7 January 2021

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

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7 January 2021

Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins

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7 January 2021

Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

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7 January 2021

Hepatitis B virus X protein activates transcription by bypassing CREB phosphorylation, not by stabilizing bZIP-DNA complexes

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7 January 2021

Analysis of the interaction between human papillomavirus type 16 E7 and the TATA-binding protein, TBP

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7 January 2021

Defective DNA repair in cells with human T-cell leukemia/bovine leukemia viruses: role of tax gene

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7 January 2021

Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA.

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7 January 2021

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

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7 January 2021

Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes

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7 January 2021

Hepatitis B virus transactivator protein X interacts with the TATA-binding protein.

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7 January 2021

Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH

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7 January 2021

Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma

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7 January 2021

Aneuploidy theory explains tumor formation, the absence of immune surveillance, and the failure of chemotherapy

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7 January 2021

SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts

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7 January 2021

Impaired nucleotide excision repair in UV-irradiated human oral keratinocytes immortalized with type 16 human papillomavirus genome

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7 January 2021

The comings and goings of nucleotide excision repair factors on damaged DNA

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7 January 2021

Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

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7 January 2021

Tax protein of human T-lymphotropic virus type I triggers DNA damage

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7 January 2021

Chromosomal abnormalities in non-Hodgkin lymphoma with peripheral T-cell type: effect of HTLV-I infection

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7 January 2021

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

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7 January 2021

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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7 January 2021

Reflections and meditations upon complex chromosomal exchanges

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7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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7 January 2021

Stomach cancer in transgenic mice expressing human papillomavirus type 16 early region genes from a keratin promoter

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7 January 2021

The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture

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7 January 2021

Induction of a BrdU-enhanceable fragile site-like lesion and sister chromatid exchanges at 11q23.1 in EBV-transformed lymphoblastoid cell lines

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7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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7 January 2021

Principles of tumor suppression

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7 January 2021

Chemotherapeutic results and prognostic factors of patients with advanced non-Hodgkin's lymphoma treated with VEPA or VEPA-M.

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7 January 2021

Ternary complex factors and cofactors are essential for human T-cell leukemia virus type 1 tax transactivation of the serum response element

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7 January 2021

Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells

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7 January 2021

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

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7 January 2021

Correct binding of viral X protein to UVDDB-p127 cellular protein is critical for efficient infection by hepatitis B viruses

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7 January 2021

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene

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7 January 2021

Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway

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7 January 2021

Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells

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7 January 2021

The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals

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7 January 2021

The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein.

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7 January 2021

Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

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7 January 2021

Significance of postnatal mother-to-child transmission of human T-lymphotropic virus type-I on the development of adult T-cell leukemia/lymphoma

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7 January 2021

A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures

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7 January 2021

Down-regulation of the INK4 family of cyclin-dependent kinase inhibitors by tax protein of HTLV-1 through two distinct mechanisms

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7 January 2021

Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding site

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7 January 2021

Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro

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7 January 2021

Differential transactivation of the intercellular adhesion molecule 1 gene promoter by Tax1 and Tax2 of human T-cell leukemia viruses.

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7 January 2021

The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

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7 January 2021

Functional inactivation but not structural mutation of p53 causes liver cancer.

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7 January 2021

Transcriptional repression of p53 by human T-cell leukemia virus type I Tax protein

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7 January 2021

Binding of the human T-cell leukemia virus Tax protein to the coactivator CBP interferes with CBP-mediated transcriptional control

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7 January 2021

Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein

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7 January 2021

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

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7 January 2021

p53 modulation of TFIIH-associated nucleotide excision repair activity

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7 January 2021

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

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7 January 2021

Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth

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7 January 2021

Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress

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7 January 2021

Hepadna virus integration generates virus-cell cotranscripts carrying 3' truncated X genes in human and woodchuck liver tumors

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7 January 2021

The retinoblastoma protein and cell cycle control

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7 January 2021

Drug-specific rearrangements of chromosome 12 in hydroxyurea-resistant mouse SEWA cells: support for chromosomal breakage model of gene amplification.

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7 January 2021

Which DNA polymerases are used for DNA-repair in eukaryotes?

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7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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7 January 2021

Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor

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7 January 2021

Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein

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7 January 2021

Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas

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7 January 2021

Identifiers

DOI

10.1002/EM.20088

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11 August 2017

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