(Q36971848)

17 August 2017

Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy (English)

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17 August 2017

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10

Derek LeRoith

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17 August 2017

Jaetaek Kim

1

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17 August 2017

Adam R Wende

2

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17 August 2017

Sandra Sena

3

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17 August 2017

Heather A Theobald

4

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17 August 2017

Jamie Soto

5

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17 August 2017

Crystal Sloan

6

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17 August 2017

Benjamin E Wayment

7

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17 August 2017

Sheldon E Litwin

8

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17 August 2017

Martin Holzenberger

9

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17 August 2017

E Dale Abel

11

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17 August 2017

18 September 2008

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17 August 2017

Molecular Endocrinology

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17 August 2017

22

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17 August 2017

11

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17 August 2017

2531-2543

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2582541/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis

1 reference

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A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

29 September 2017

1 reference

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The fuzzy logic of physiological cardiac hypertrophy

29 September 2017

1 reference

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Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway

29 September 2017

1 reference

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Regulating insulin signaling and beta-cell function through IRS proteins

29 September 2017

1 reference

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Akt2 regulates cardiac metabolism and cardiomyocyte survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Regulation of cardiac hypertrophy by intracellular signalling pathways

29 September 2017

1 reference

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AMPK alterations in cardiac physiology and pathology: enemy or ally?

29 September 2017

1 reference

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Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart

29 September 2017

1 reference

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Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

29 September 2017

1 reference

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Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

29 September 2017

1 reference

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Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5

29 September 2017

1 reference

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An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

A role for the transcriptional coactivator PGC-1alpha in muscle refueling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

IGF-I does not prevent myotube atrophy caused by proinflammatory cytokines despite activation of Akt/Foxo and GSK-3beta pathways and inhibition of atrogin-1 mRNA.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

c-myc-induced hepatocarcinogenesis in the absence of IGF-I receptor.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Physiological role of AMP-activated protein kinase in the heart: graded activation during exercise

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Increased cardiac sympathetic activity and insulin-like growth factor-I formation are associated with physiological hypertrophy in athletes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2582541

Cardiac adaptations to chronic exercise in mice

4 September 2018

1 reference

12 December 2020

Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle

1 reference

12 December 2020

Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout

1 reference

12 December 2020

Akt1 is required for physiological cardiac growth

1 reference

12 December 2020

Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice

1 reference

12 December 2020

Distribution of chimeric IGF binding protein (IGFBP)-3 and IGFBP-4 in the rat heart: importance of C-terminal basic region

1 reference

12 December 2020

Short- and long-term swimming exercise training increases myocardial insulin-like growth factor-I gene expression

1 reference

12 December 2020

Calcium induces increases in peroxisome proliferator-activated receptor gamma coactivator-1alpha and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation

1 reference

12 December 2020

Cardiac hypertrophy caused by peroxisome proliferator- activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling

1 reference

12 December 2020

The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2008-0265

1 reference

17 August 2017

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17 August 2017

1 reference