(Q36974272)

17 August 2017

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title

Mutations of mitochondrial DNA - cause or consequence of the ageing process? (English)

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17 August 2017

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Meissner C

1

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17 August 2017

publication date

1 October 2007

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Zeitschrift fuer Gerontologie und Geriatrie

17 August 2017

published in

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17 August 2017

volume

40

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17 August 2017

issue

5

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17 August 2017

page(s)

325-333

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Mitochondrial DNA in aging and degenerative disease

17 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00391-007-0481-Z

The biologic clock: the mitochondria?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00391-007-0481-Z

Human aging is associated with stochastic somatic mutations of mitochondrial DNA.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00391-007-0481-Z

Clonal expansions of mitochondrial genomes: implications for in vivo mutational spectra.

21 January 2018

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Mitochondrial DNA synthesis studied autoradiographically in various cell types in vivo

21 January 2018

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Mitochondrial DNA repair and aging

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00391-007-0481-Z

FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

21 January 2018

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The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice

21 January 2018

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12 December 2020

Experimental evidence against the mitochondrial theory of aging. A study of isolated human skeletal muscle mitochondria

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12 December 2020

The mitochondrial genome: mutation, selection and recombination.

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12 December 2020

Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys.

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12 December 2020

Multiple deletions of mtDNA remove the light strand origin of replication

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12 December 2020

Mitochondrial DNA damage and the aging process: facts and imaginations.

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12 December 2020

Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?

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12 December 2020

Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers

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Mitochondrial disease in superoxide dismutase 2 mutant mice

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12 December 2020

Mitochondria, oxygen free radicals, disease and ageing

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Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone

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12 December 2020

The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in humans and mice

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12 December 2020

Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells

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12 December 2020

Random mtDNA deletions and functional consequence in aged human skeletal muscle

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12 December 2020

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

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12 December 2020

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

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Mitochondrial point mutations do not limit the natural lifespan of mice.

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12 December 2020

Mitochondrial DNA mutations and aging: a case closed?

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12 December 2020

The role of mitochondrial DNA mutations in mammalian aging

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12 December 2020

Nuclear genes in mitochondrial disorders.

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12 December 2020

Oxidative damage and mitochondrial decay in aging

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12 December 2020

Mitochondrial role in cell aging

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12 December 2020

The mitochondrial theory of aging: dead or alive?

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12 December 2020

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12 December 2020

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

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12 December 2020

Double-strand breaks of mouse muscle mtDNA promote large deletions similar to multiple mtDNA deletions in humans

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12 December 2020

Decreases in protective enzymes correlates with increased oxidative damage in the aging mouse brain.

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12 December 2020

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

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12 December 2020

Differential occurrence of mutations in mitochondrial DNA of human skeletal muscle during aging

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12 December 2020

Age-dependent increase of mitochondrial DNA deletions together with lipid peroxides and superoxide dismutase in human liver mitochondria

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12 December 2020

Extension of murine life span by overexpression of catalase targeted to mitochondria

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Microglia as neuroprotective, immunocompetent cells of the CNS.

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12 December 2020

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

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12 December 2020

Accumulation of deletions in human mitochondrial DNA during normal aging: analysis by quantitative PCR

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12 December 2020

The mitochondrial theory of aging: do damaged mitochondria accumulate by delayed degradation?

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12 December 2020

Analysis of repeat-mediated deletions in the mitochondrial genome of Saccharomyces cerevisiae

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12 December 2020

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

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12 December 2020

Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age.

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12 December 2020

Oxidized, deaminated cytosines are a source of C --> T transitions in vivo

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12 December 2020

Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients.

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12 December 2020

Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states

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12 December 2020

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

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12 December 2020

Topology of superoxide production from different sites in the mitochondrial electron transport chain

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12 December 2020

Neurodegeneration and aging: role of the second genome

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12 December 2020

Measurement of the 4,834-bp mitochondrial DNA deletion level in aging rat liver and brain subjected or not to caloric restriction diet

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12 December 2020

Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle

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12 December 2020

Mitochondrial DNA deletions and the aging heart

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12 December 2020

Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation

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12 December 2020

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

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12 December 2020

Quantification and sequencing of somatic deleted mtDNA in single cells: evidence for partially duplicated mtDNA in aged human tissues

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12 December 2020

Mitochondrial DNA mutations in human colonic crypt stem cells

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12 December 2020

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

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12 December 2020

Deltoid human muscle mtDNA is extensively rearranged in old age subjects

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12 December 2020

10.1007/S00391-007-0481-Z

Identifiers

DOI

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17 August 2017

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