(Q36978855)

17 August 2017

The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains (English)

1 reference

17 August 2017

Orthoebolavirus zairense

0 references

1 reference

6

Richard A Koup

1 reference

17 August 2017

Alexander N. Freiberg

5

object named as

Alexander N Freiberg

1 reference

17 August 2017

Ndongala M Lubaki

1

1 reference

17 August 2017

Philipp Ilinykh

2

1 reference

17 August 2017

Colette Pietzsch

3

1 reference

17 August 2017

Bersabeh Tigabu

4

1 reference

17 August 2017

Alexander Bukreyev

7

1 reference

17 August 2017

language of work or name

English

0 references

publication date

24 April 2013

1 reference

17 August 2017

15

1 reference

inferred from page(s)

published in

Journal of Virology

1 reference

17 August 2017

87

1 reference

17 August 2017

13

1 reference

17 August 2017

7471-7485

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3700277/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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Human BM stem cells initiate angiogenesis in human islets in vitro

29 September 2017

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Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis

29 September 2017

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Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function

29 September 2017

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Hypoxia: A Link between Fibrogenesis, Angiogenesis, and Carcinogenesis in Liver Disease

29 September 2017

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CD8+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells

29 September 2017

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STAT1 and pathogens, not a friendly relationship

29 September 2017

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29 September 2017

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Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus

29 September 2017

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Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

29 September 2017

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Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

29 September 2017

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Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling

29 September 2017

1 reference

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The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide.

29 September 2017

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Evasion of interferon responses by Ebola and Marburg viruses

29 September 2017

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29 September 2017

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Infection and maturation of monocyte-derived human dendritic cells by human respiratory syncytial virus, human metapneumovirus, and human parainfluenza virus type 3

29 September 2017

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Structure of the Ebola VP35 interferon inhibitory domain

29 September 2017

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Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge

29 September 2017

1 reference

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Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein

29 September 2017

1 reference

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Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge

29 September 2017

1 reference

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Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

29 September 2017

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Ebola sGP--the first viral glycoprotein shown to be C-mannosylated

29 September 2017

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Successful topical respiratory tract immunization of primates against Ebola virus

29 September 2017

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Ebola virus infection of human PBMCs causes massive death of macrophages, CD4 and CD8 T cell sub-populations in vitro.

29 September 2017

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The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity

29 September 2017

1 reference

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Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses.

29 September 2017

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Reverse genetic generation of recombinant Zaire Ebola viruses containing disrupted IRF-3 inhibitory domains results in attenuated virus growth in vitro and higher levels of IRF-3 activation without inhibiting viral transcription or replication

29 September 2017

1 reference

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Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

29 September 2017

1 reference

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Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

29 September 2017

1 reference

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A single intranasal inoculation with a paramyxovirus-vectored vaccine protects guinea pigs against a lethal-dose Ebola virus challenge

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Generation of eGFP expressing recombinant Zaire ebolavirus for analysis of early pathogenesis events and high-throughput antiviral drug screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Ebola virus glycoprotein toxicity is mediated by a dynamin-dependent protein-trafficking pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

A C-terminal basic amino acid motif of Zaire ebolavirus VP35 is essential for type I interferon antagonism and displays high identity with the RNA-binding domain of another interferon antagonist, the NS1 protein of influenza A virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Ebola and Marburg virus-like particles activate human myeloid dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Ebola virus-like particles protect from lethal Ebola virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Reverse genetics demonstrates that proteolytic processing of the Ebola virus glycoprotein is not essential for replication in cell culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Development of a preventive vaccine for Ebola virus infection in primates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Downregulation of beta1 integrins by Ebola virus glycoprotein: implication for virus entry.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

The Ebola virus VP35 protein functions as a type I IFN antagonist.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Activation of the p38 mitogen-activated protein kinase by type I interferons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Biochemical analysis of the secreted and virion glycoproteins of Ebola virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Processing of the Ebola virus glycoprotein by the proprotein convertase furin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Inflammatory infiltration of the upper airway epithelium during Sendai virus infection: involvement of epithelial dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Characterization of filoviruses based on differences in structure and antigenicity of the virion glycoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Inhibition of protein kinase C by a peptide conjugate homologous to a domain of the retroviral protein p15E

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

The envelope glycoprotein of Ebola virus contains an immunosuppressive-like domain similar to oncogenic retroviruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Ebola haemorrhagic fever in Zaire, 1976

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Nuclear export determines the cytokine sensitivity of STAT transcription factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Homotypic cluster formation of dendritic cells, a close correlate of their state of maturation. Defects in the biobreeding diabetes-prone rat.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700277

Dendritic cells cross-dressed with peptide MHC class I complexes prime CD8+ T cells

4 December 2018

1 reference

12 December 2020

Dendritic cells promote T-cell survival or death depending upon their maturation state and presentation of antigen

1 reference

12 December 2020

Functional involvement of E-cadherin in TGF-beta 1-induced cell cluster formation of in vitro developing human Langerhans-type dendritic cells

1 reference

12 December 2020

Rescue by cytokines of apoptotic cell death induced by IL-2 deprivation of human antigen-specific T cell clones

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.03316-12

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23616668

1 reference