(Q36981715)

17 August 2017

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title

Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases (English)

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17 August 2017

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Damien J Keating

1

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17 August 2017

language of work or name

English

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publication date

25 October 2007

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Journal of Neurochemistry

17 August 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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17 August 2017

volume

104

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17 August 2017

issue

2

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17 August 2017

page(s)

298-305

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p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

1 reference

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Quantification of synapse formation and maintenance in vivo in the absence of synaptic release

21 January 2018

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Long-term potentiation enhances neurogenesis in the adult dentate gyrus.

21 January 2018

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Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

SNAP25 is a pre-synaptic target for the depressant action of reactive oxygen species on transmitter release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Resolution of regulated secretion into sequential MgATP-dependent and calcium-dependent stages mediated by distinct cytosolic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

APP processing and synaptic function

21 January 2018

1 reference

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Oxygen-sensing pathway for SK channels in the ovine adrenal medulla.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Modulation of protein kinases and protein phosphatases by reactive oxygen species: implications for hippocampal synaptic plasticity

21 January 2018

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Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Gene regulation and DNA damage in the ageing human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Abnormalities in the synaptic vesicle fusion machinery in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Dietary supplementation with vitamin E reverses the age-related deficit in long term potentiation in dentate gyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Selective increase in cellular A beta 42 is related to apoptosis but not necrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Plasticity-induced growth of dendritic spines by exocytic trafficking from recycling endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Reactive oxygen species and synaptic plasticity in the aging hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Molecular and synaptic changes in the hippocampus underlying superior spatial abilities in pre-symptomatic G93A+/+ mice overexpressing the human Cu/Zn superoxide dismutase (Gly93 --> ALA) mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Synaptic assembly of the brain in the absence of neurotransmitter secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Role of alpha-synuclein in presynaptic dopamine recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

Redox-sensitive extracellular gates formed by auxiliary β subunits of calcium-activated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04997.X

10.1111/J.1471-4159.2007.04997.X

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference