(Q36984884)

17 August 2017

1 reference

title

Primer: signal transduction in rheumatic disease--a clinician's guide (English)

1 reference

17 August 2017

Susan E Sweeney

1

1 reference

PubMed ID

17968336

17 August 2017

Gary S Firestein

series ordinal

2

1 reference

17 August 2017

1 November 2007

1 reference

Nature Clinical Practice Rheumatology

17 August 2017

1 reference

17 August 2017

3

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17 August 2017

11

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17 August 2017

651-660

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https://scigraph.springernature.com/pub.10.1038/ncprheum0631

17 August 2017

0 references

cites work

Expression and activation of mitogen-activated protein kinase kinases-3 and -6 in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

Regulation of c-Jun phosphorylation by the I kappa B kinase-epsilon complex in fibroblast-like synoviocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

Immunostimulatory DNA sequences influence the course of adjuvant arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Targeting JNK for therapeutic benefit: from junk to gold?

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Regulation of JNK by MKK-7 in fibroblast-like synoviocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthr

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Flow cytometric assessment of the signaling status of human B lymphocytes from normal and autoimmune individuals

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Signal transduction networks in rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Interferon pathway activation in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Antiviral gene expression in rheumatoid arthritis: role of IKKepsilon and interferon regulatory factor 3.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

The emerging role of interferon in human systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Toll-like receptor function and signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

1 reference

7 January 2021

Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Vascular dendritic cells in giant cell arteritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Molecular identification of a danger signal that alerts the immune system to dying cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

PI3K in lymphocyte development, differentiation and activation

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0631

7 January 2021

Identifiers

DOI

10.1038/NCPRHEUM0631

1 reference

PubMed ID

17968336

Dimensions Publication ID

17 August 2017

0 references

1 reference

PubMed ID

17968336