(Q36993430)

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Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria

scientific article published on 08 September 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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pharmacokinetics

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Michael Alifrangis

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Jørgen Anders Lindholm Kurtzhals

7

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Europe PubMed Central

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13 January 2020

Jørgen Anders Lindholm Kurtzhals

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Kurtzhals, J.A.L.

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George O Adjei

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Kim Kristensen

2

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13 January 2020

Bamenla Q Goka

3

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Europe PubMed Central

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13 January 2020

Lotte C G Hoegberg

4

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Europe PubMed Central

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13 January 2020

Onike P Rodrigues

6

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Europe PubMed Central

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13 January 2020

Adiku, T.K.

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Adjei, G.O.

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Kristensen, K.

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Goka, B.Q.

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Hoegberg, L.C.

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Alifrangis, M.

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Rodrigues, O.P.

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Kurtzhals, J.A.

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Hoegberg, L.C.G.

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8 September 2008

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13 January 2020

2008

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number of pages

7

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Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

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13 January 2020

52

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Europe PubMed Central

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13 January 2020

12

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Europe PubMed Central

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13 January 2020

4400-4406

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

http://ugspace.ug.edu.gh/handle/123456789/879

0 references

Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Short communication: high prevalence of the cytochrome P450 2C8*2 mutation in Northern Ghana

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Molecular determination of point mutation haplotypes in the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum in three districts of northern Tanzania

1 reference

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29 September 2017

Combination of drug level measurement and parasite genotyping data for improved assessment of amodiaquine and sulfadoxine-pyrimethamine efficacies in treating Plasmodium falciparum malaria in Gabonese children

1 reference

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29 September 2017

Epidemiology of drug-resistant malaria

1 reference

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29 September 2017

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

How can we do pharmacokinetic studies in the tropics?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

The xenobiotic inhibitor profile of cytochrome P4502C8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

The human CYP2C locus: a prototype for intergenic and exon repetition splicing events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Averting a malaria disaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Antimalarial 4-aminoquinolines: mode of action and pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Pharmacokinetics of mefloquine alone or in combination with artesunate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Pharmacokinetics of intravenous amodiaquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Amodiaquine induced agranulocytosis and liver damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

The disposition of amodiaquine in Zambians and Nigerians with malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

29 September 2017

Population pharmacokinetics of amodiaquine and desethylamodiaquine in pediatric patients with uncomplicated falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

27 June 2018

Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

27 June 2018

Disposition of amodiaquine and related antimalarial agents in human neutrophils: implications for drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

27 June 2018

Pharmacokinetic and pharmacodynamic study of amodiaquine and its two metabolites after a single oral dose in human volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

27 June 2018

Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

27 June 2018

A comparison of the in vitro activities of amodiaquine and desethylamodiaquine against isolates of Plasmodium falciparum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

27 June 2018

Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

4 September 2018

CYP2C8 polymorphism frequencies among malaria patients in Zanzibar.

1 reference

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4 September 2018

Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

4 September 2018

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

4 September 2018

Hepatotoxicity Due to a Drug Interaction between Amodiaquine plus Artesunate and Efavirenz

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592852

20 October 2018

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4 December 2018

Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/18779360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amodiaquine as a prodrug: importance of metabolite(s) in the antimalarial effect of amodiaquine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18779360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation, characterization and standardization of a major metabolite of amodiaquine by chromatographic and spectroscopic methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/18779360

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00673-07

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18779360%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

University of Ghana Digital Collections (UGSpace) ID

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